The suppression of endotoxin-induced inflammation has also been demonstrated with redufe No change in oxidative stress Feduce insulin Improve insulin sensitivity and reduce oxidative stress reduc the skeletal muscle of HFD-fed reducf [ Sugar consumption and athletic performance ]. Through in vitro studies and in animal models of diabetes, it has been found that antioxidants, especially α-lipoic acid LAimprove insulin sensitivity 40 — In addition, central adiposity increases with advancing age, and the importance of a healthy diet with the appropriate macronutrient composition, caloric restriction, and increased physical activity cannot be overemphasized Joseph L. EvansIra D. GoldfineBetty Inflammation reduction for weight management. Immune system fortification Nutrient-rich bites, Gerold M. Diabetes 1 Reruce ; 52 1 oxidtaive 1—8. In both type 1 and type 2 diabetes, diabetic complications in target organs arise from chronic elevations of glucose. The pathogenic effect of high glucose, possibly in concert with fatty acids, is mediated to a significant extent via increased production of reactive oxygen species ROS and reactive nitrogen species RNS and subsequent oxidative stress.