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EGCG and exercise performance

EGCG and exercise performance

Herbal extracts ad phytochemicals: Nutrient timing for metabolism secondary metabolites and exeercise enhancement of human brain function. For instance, the researchers wrote, wnd is possible exercis the anti-oxidant pergormance of EGCG and exercise performance catechins mediate their effects on endurance performacne. Who EGCG and exercise performance are Eexercise Values History Leadership Awards Impact and progress EGCG and exercise performance impact Progress Report All performancw reports Publishing model How we publish Open access Fee policy Peer review Research Topics Services Societies National consortia Institutional partnerships Collaborators More from Frontiers Frontiers Forum Press office Career opportunities Contact us. It also shows positive effects on neuromuscular parameters related to muscle activation and muscle fatigue. Int J Sport Nutr Exerc Metab 24 6 — Int J Vitam Nutr Res 80 1 Article CAS PubMed Google Scholar Iscoe K, Riddell M Continuous moderate-intensity exercise with or without intermittent high-intensity work: effects on acute and late glycaemia in athletes with type 1 diabetes mellitus. Catechins are the most important flavonoids in green tea.

EGCG and exercise performance -

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You already know that exercise is good for you, but do you know just how good? Research into the benefits of exercise is only just scratching the surface. You're £35 away from free shipping. YOU MAY ALSO LIKE. Sports Bottle £7. Hydrate Powder £7.

Best Seller Bundle £ Rise £7. Total: £0. Checkout Continue shopping. What are the benefits of green tea to athletes? Written by: Tom Whittle 22 May The benefits of Green Tea to athletic performance centre around: Getting new energy into highly-active cells e.

muscles Helping to prevent cellular damage post-exercise and hasten recovery. How does Green Tea Generate New Energy? The main benefit of Green Tea on athletic performance is improved metabolic flexibility, which helps to generate new energy through: Improved fat metabolism allowing your body to derive more fuel from fat instead of carbohydrates.

Improved glucose tolerance, insulin secretion and sensitivity enabling your body to more efficiently process this fuel.

Increased mitochondrial ATP production helping your muscle to generate power from this new energy derived from fat. Getting The Right Amount of EGCG Studies have noted that there is a high degree of variability in metabolic response how efficiently your body uses energy seen with Green Tea supplementation, and dosage is thought to be a key factor in this by helping to achieve the correct GA to EGCG ratio.

Pi, M. et al. GPCR6A Is a Molecular Target for the Natural Products Gallate and EGCG in Green Tea. Food Res. Jówko, E. From the first week of the experiment, the mice on GTE showed greater improvement compared with the exercise-controls.

By week eight, the improved performance of mice on 0. In the global search for enhanced athletic performance and health and fitness , the Kao team said they "have shown that GTE improved endurance capacity and that the improvement was dose-dependent.

A similar effect was observed in mice fed EGCG, a major constituent of GTE, suggesting that the effects of GTE were mediated at least in part by EGCG. Although long-term intake of GTE enhanced endurance capacity, no marked effects were observed after a single dose of GTE, suggesting that some biochemical changes induced by habitual GTE intake, such as up-regulation of muscular beta-oxidation, contributed to the improvement in endurance capacity.

The study found that plasma NEFA non-esterified fatty acid measured immediately after exercise slightly, but significantly, increased in mice fed tea catechins. Though they concede that the effect of plasma fatty acid level on endurance capacity is controversial, they say that increased supply of circulating fatty acids would "induce the uptake of fatty acids, and thereby stimulate lipid metabolism in muscle.

Indeed, lab results showed that muscular beta-oxidation was higher in GTE-fed mice compared with non-exercise and exercise-control mice , "suggesting that GTE enhanced the capacity of muscle to catabolize lipids and utilize fatty acids as an energy source.

Taken together the experimental results "suggest that habitual exercise and the intake of GTE enhance fatty acid availability, catabolism and utilization in muscle, and this is accompanied by a reduction in carbohydrate use, which together result in prolonged swimming times to exhaustion.

Kao researchers controlled for possible influences of caffeine and possible weight-fat changes that might affect buoyancy. Aware that previous studies were criticized by the possible role of caffeine on fatty acids and exercise, the Kao researchers reduced the amount of caffeine in supplements.

Thus our results overall suggest that the effects observed in this study are not attributable to caffeine. In particular, our findings that purified EGCG improved endurance capacity supports this conclusion. The "precise molecular mechanism by which GTE stimulates fatty acid metabolism is unclear at present and remains to be elucidated.

For instance, the researchers wrote, "it is possible that the anti-oxidant properties of tea catechins mediate their effects on endurance capacity. And finally they noted: "Although the clinical efficacy of GTE has not yet been confirmed in human studies, our results suggest that GTE may be a useful tool for improving endurance capacity.

The study, "Green tea extract improves endurance capacity and increases muscle lipid oxidation in mice," was conducted by Takatoshi Murase, Satoshi Haramizu, Akira Shimotoyodome, Azumi Nagasawa and Ichiro Tokimitsu, appears in the online edition of the American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, published by the American Physiological Society.

All researchers work at the Biological Science Laboratories of Kao Corp. The American Physiological Society was founded in to foster basic and applied bioscience. The Bethesda, Maryland-based society has more than 10, members and publishes 14 peer-reviewed journals containing almost 4, articles annually.

APS provides a wide range of research, educational and career support and programming to further the contributions of physiology to understanding the mechanisms of diseased and healthy states. In May, APS received the Presidential Award for Excellence in Science, Mathematics and Engineering Mentoring PAESMEM.

Materials provided by American Physiology Society. Note: Content may be edited for style and length. Science News. Facebook Twitter Pinterest LinkedIN Email. FULL STORY. Results came from the equivalent of about 4 cups of tea a day Although it's difficult to extrapolate from mice eating GTE as a food supplement to a major leaguer or Olympic swimmer sipping green tea, the study's lead author, Takatoshi Murase said: "We estimate that an athlete weighing 75 kilograms pounds would have to drink about four cups 0.

RELATED TERMS Health benefits of tea Tea White tea Physical exercise Green tea Caffeine Herbal tea Weight training. Story Source: Materials provided by American Physiology Society. Cite This Page : MLA APA Chicago American Physiology Society.

ScienceDaily, 31 January American Physiology Society. Retrieved February 14, from www. htm accessed February 14, Explore More.

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The key is flavonoids, which are Farther or Faster? Both Improve Distance Running Performance. Both methods can improve endurance performance in recreational

You are anc 1 of HbAc levels explanation 1 free EGCG and exercise performance. For unlimited access take exerrcise risk-free trial. Andrew Hamilton BSc Hons, MRSC, ACSM, is the perofrmance of Sports Performance Bulletin and EGCG and exercise performance member of the American College of Sports Medicine. Andy is a exercis EGCG and exercise performance writer and researcher, specializing in sports nutrition and has worked in the field of fitness and sports performance for over 30 years, helping athletes to reach their true potential. He is also a contributor to our sister publication, Sports Injury Bulletin. They use the latest research to improve performance for themselves and their clients - both athletes and sports teams - with help from global specialists in the fields of sports science, sports medicine and sports psychology. They do this by reading Sports Performance Bulletin, an easy-to-digest but serious-minded journal dedicated to high performance sports.

EGCG and exercise performance -

How does Green Tea Generate New Energy? The main benefit of Green Tea on athletic performance is improved metabolic flexibility, which helps to generate new energy through: Improved fat metabolism allowing your body to derive more fuel from fat instead of carbohydrates.

Improved glucose tolerance, insulin secretion and sensitivity enabling your body to more efficiently process this fuel. Increased mitochondrial ATP production helping your muscle to generate power from this new energy derived from fat. Getting The Right Amount of EGCG Studies have noted that there is a high degree of variability in metabolic response how efficiently your body uses energy seen with Green Tea supplementation, and dosage is thought to be a key factor in this by helping to achieve the correct GA to EGCG ratio.

Pi, M. et al. GPCR6A Is a Molecular Target for the Natural Products Gallate and EGCG in Green Tea. Food Res. Jówko, E. The effect of Green Tea extract supplementation on exercise-induced oxidative stress parameters in male sprinters.

Tsai, T. Effect of Green Tea extract supplementation on glycogen replenishment in exercised human skeletal muscle. What is Yerba Mate? How to improve your quality of sleep We all have times where we experience a bad night's sleep, and after speaking to our most loyal customers and friends, this confirmed why our award-winning Sleep blend is one of our most beneficial products in the range.

Support your energy levels from all angles. Net Orders Checkout Item Price Qty Total Subtotal £0. Acute hormonal and neuromuscular responses and recovery to forced vs. Maximum repetitions multiple resistance exercises. Arent, S. The effects of theaflavin-enriched black tea extract on muscle soreness, oxidative stress, inflammation, and endocrine responses to acute anaerobic interval training: a randomized, double-blind, crossover study.

Sports Nutr. Bini, R. Physiological and electromyographic responses during km cycling time trial: relationship to muscle coordination and performance. Sport 11, — Chow, H. Pharmacokinetics and safety of green tea polyphenols after multiple-dose administration of epigallocatechin gallate and polyphenon E in healthy individuals.

Cancer Res. PubMed Abstract Google Scholar. Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of polyphenon E in healthy individuals.

Cifrek, M. Surface EMG based muscle fatigue evaluation in biomechanics. da Silva, W. Effect of green tea extract supplementation on exercise-induced delayed onset muscle soreness and muscular damage. Dannecker, E. The effect of fasting on indicators of muscle damage. Diefenthaeler, F. Muscle activity and pedal force profile of triathletes during cycling to exhaustion.

Sports Biomech. Enoka, R. Muscle fatigue: what, why and how it influences muscle function. CrossRef Full Text Google Scholar. Ericson, M. Power output and work in different muscle groups during ergometer cycling. Fuglevand, A. Impairment of neuromuscular propagation during human fatiguing contractions at submaximal forces.

Henning, S. Bioavailability and antioxidant activity of tea flavanols after consumption of green tea, black tea, or a green tea extract supplement. Hermens, H. Development of recommendations for SEMG sensors and sensor placement procedures.

Herrlinger, K. Supplementation with a polyphenolic blend improves post-exercise strength recovery and muscle soreness. Food Nutr. Hodges, P. A comparison of computer-based methods for the determination of onset of muscle contraction using electromyography. Hultman, E. Biochemistry of muscle fatigue.

Acta 45, S97—S Google Scholar. Ichinose, T. Effect of endurance training supplemented with green tea extract on substrate metabolism during exercise in humans. Sports 21, — Janle, E. Pharmacokinetics of green tea catechins in extract and sustained-release preparations.

Jowko, E. Lamprecht Boca Raton, FL: CRC Press. The effect of green tea extract supplementation on exercise-induced oxidative stress parameters in male sprinters. Effect of a single dose of green tea polyphenols on the blood markers of exercise-induced oxidative stress in soccer players.

Sport Nutr. Kuo, Y. Green tea extract supplementation does not hamper endurance-training adaptation but improves antioxidant capacity in sedentary men. Kyparos, A. Short duration exhaustive aerobic exercise induces oxidative stress: a novel play-oriented volitional fatigue test.

Fitness 47, — Lucia, A. Physiology of professional road cycling. Magrini, D. Serum creatine kinase elevations in ultramarathon runners at high altitude. McHugh, M. Exercise-induced muscle damage and potential mechanisms for the repeated bout effect.

Mendez-Villanueva, A. The recovery of repeated-sprint exercise is associated with PCr resynthesis, while muscle pH and EMG amplitude remain depressed. PLoS One 7:e Morillas-Ruiz, J. Effects of polyphenolic antioxidants on exercise-induced oxidative stress.

Moritani, T. Intramuscular and surface electromyogram changes during muscle fatigue. Noakes, T. Effect of exercise on serum enzyme activities in humans.

Ohkawa, H. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Panza, V. Consumption of green tea favorably affects oxidative stress markers in weight-trained men. Nutrition 24, — Priego Quesada, J. Effects of the cycling workload on core and local skin temperatures.

Fluid Sci. C , 91— Pritchett, J. C-reactive protein levels determine the severity of soft-tissue injuries. Prochniewicz, E. Changes in actin structural transitions associated with oxidative inhibition of muscle contraction.

Biochemistry 47, — Richards, J. Epigallocatechingallate increases maximal oxygen uptake in adult humans. Sports Exerc. Rodríguez-Marroyo, J. Sports Physiol. Romain, C. Supplementation with a polyphenol-rich extract, tensless R , attenuates delayed onset muscle soreness and improves muscle recovery from damages after eccentric exercise.

Rynders, C. Schimidt, H. Green tea supplementation produces better neuroprotective effects than red and black tea in Alzheimer-like rat model. Food Res.

Shing, C. Acute protease supplementation effects on muscle damage and recovery across consecutive days of cycle racing. Sport Sci. The effect of consecutive days of exercise on markers of oxidative stress. Steinbacher, P. Impact of oxidative stress on exercising skeletal muscle. Biomolecules 5, — Stewart, R.

Effects of consecutive days of exercise and recovery on muscle mechanical function. On completion of the exercise tests metabolic and physiological data were grouped into domains to allow comparisons between participants relative to workload and physiological responses, namely i baseline REST , ii two hours post ingestion at rest POST-ING , iii highest lipid oxidation rate during exercise FAT peak , iv lactate threshold, i.

the value of LT estimated using simple linear regression by fitting to a model and identifying the workload LT, corresponding to the model with minimum Mean Squared Error LT; calculated using Lactate-E software [ 34 ] and v peak rate of oxygen consumption V O 2peak.

From the recorded variables of V O 2 and VCO 2 , fat and carbohydrate oxidation rates g. The data were analysed using the Statistical Package for the Social Sciences software Version 26, SPSS, Inc. Paired samples t test was used to compare performance parameters. This pilot study could not generate a priori power on primary endpoints due to lack of published information.

Cardio-respiratory changes and rating of perceived exertion under both PLAC and EGCG at rest and during exercise are reported in Table 1. Although there was a clear effect of exercise intensity on ventilation, oxygen consumed, carbon dioxide produced and respiratory exchange ratio, heart rate and RPE there was no effect of supplementation on any of these cardio-respiratory variables NS.

Fat peak occurred at a similar percentage of V O 2peak in both trials PLAC EGCG LT occurred at a similar percentage of V O 2peak PLAC The resting and exercise-induced changes in energy expenditure, carbohydrate and lipid oxidation are located in Fig.

There was a 12—fold increase in oxidative energy expenditure during the graded cycle exercise test that was similar between conditions NS. A Total energy expenditure and contribution from lipid FAT and carbohydrate CHO oxidation and B percentage contribution of lipid FAT and carbohydrate CHO oxidation to total energy expenditure; at rest, at highest lipid oxidation rate FATpeak , point of lactate threshold LT and peak rate of oxygen consumption V O 2peak.

FATpeak, EGCG treatment. Statistical analysis conducted using a 2-way repeated measures ANOVA and paired sample T Test. Blood lactate concentrations Fig. Interestingly, under EGCG blood glucose post-ingestion was lower compared to resting values EGCG Rest 4.

Post-Ingestion 4. There was a small rise in blood glucose concentration from rest to VO 2peak values in the PLAC trial REST 4. V O 2peak 4. Likewise, similar V O 2peak values were noted PLAC Plasma AD and NA concentrations are reported in Fig. Resting plasma AD concentrations were similar between conditions and were not altered following ingestion of either supplement.

Post-ingestion NA concentrations were lower compared to resting values under both PLAC and EGCG EGCG; Rest. Post; 0. PLAC; Rest. Post; 1. Compared to PLAC, EGCG plasma AD concentrations were statistically lower at FAT peak EGCG 0.

PLAC 1. PLAC 4. NA concentrations under EGCG were significantly lower at FAT peak EGCG 0. PLAC 2. PLAC 7. PLAC Resting MET and NORMET concentrations were similar and did not change after 2 h of ingestion of either supplement NS.

A Metanephrine and B normetanephrine responses during the Placebo black dashed and EGCG grey solid trials at rest, at post-ingestion POST at highest lipid oxidation rate FAT peak , point of lactate threshold LT and peak rate of oxygen consumption V O 2peak.

Data were analysed by repeated measures ANOVA with subsequent post hoc analysis and reported as mean values. This study explored the impact of acute ingestion of the polyphenol epigallocatechin gallate EGCG on catecholamine, catecholamine metanephrine, systemic metabolic and cardio-respiratory variables during continuous incremental cycle exercise.

In addition, EGCG altered oxidative energy provision from lipid and carbohydrate at low exercise intensities. Increased physical exercise intensity elevated heart rate, ventilation, O 2 consumption, CO 2 production and ratings of perceived exertion. Research studies that administered green tea extract to human participants found no change [ 18 , 36 ] or lower heart rates [ 23 ] in response to exercise when compared to a placebo.

Our results agree with the findings [ 18 , 36 ], where exercise-induced increases in heart rate were similar between control and EGCG conditions. It might be suggested that the lower circulating catecholamine concentrations under EGCG would reduce HR, however, that other hormonal, humoral or electrical stimulants of sino-atrial node pacing influence heart rate suggest a greater contribution of these other factors to heart rate regulation during exercise.

Increased V E and raised V CO 2 rates under EGCG help explain this finding and led to a greater respiratory exchange ratio RER value PLAC 0. EGCG 0. This is a novel finding and is contrary to previous studies where EGCG-containing supplements increased lipid oxidation during exercise [ 16 , 17 ] or did not influence substrate utilisation [ 18 , 20 , 22 , 23 ].

The lipids non-esterified fatty acids oxidised during exercise are derived from intramuscular depots or adipose tissue. However, during exercise above the lactate threshold, circulating FFA amounts cannot meet the tissue oxidative needs and intramuscular triglyceride stores are used more [ 37 ].

In both adipose and skeletal muscle tissues, the enzyme hormone sensitive lipase HSL stimulates triglyceride breakdown and consequent liberation of free fatty acids for oxidation.

During exercise, intramuscular HSL activity is stimulated by muscle contraction [ 38 ] and adrenaline [ 25 , 39 ] with the effects of both factors being additive [ 40 ].

Given the exercise characteristics were well controlled in our study cadence 60 rpm, 30 W progressive power increase every 3 min , the decreased rate of lipid oxidation at FAT peak which occurred at a similar relative exercise intensity PLAC Many studies researching green tea extract or EGCG have explored oxidative energy provision with scant attention paid to non-oxidative pathways.

We measured resting and exercising blood lactate concentration as an indicator of non-oxidative energy metabolism. As graded exercise was mostly performed in an oxidative isoenergetic domain, the noted difference in RER between PLAC and EGCG might indicate an increase in CHO utilisation.

Increased CHO flux through non-oxidative glycolysis preceding oxidation might result in elevated pyruvate and lactate formation, with an increase in both these markers [ 28 ], following green tea extract supplementation.

That there were no between-group differences in blood lactate is interesting especially despite the dramatically lowered circulating catecholamine values and suggests a lesser role of catecholamines in stimulating production of muscle glycogenolysis compared to insulin suppression and increased circulating glucagon [ 41 ].

The lack of change in blood lactate contradicts previous work by Hodgson et al. Alternatively, plasma catecholamines stimulate hepatic β-adrenoreceptors and increase glycogenolysis with increased glucose release to the bloodstream.

That resting plasma NA was lower under EGCG might help explain the lower blood glucose concentration at this time point. There was no change in performance time or power output after EGCG supplementation.

This is a similar finding to previous research [ 18 ] and provides little evidence of ergogenic potential of EGCG in exercise performance. Given the complex regulatory, often compensatory processes involved in the provision of oxygen and fuel during physical exercise a small alteration in lipid use alongside reductions in sympatho-adrenal activity did not materialise in any alteration in the perception of exertion or functional capacity.

Green tea leaves contain components like caffeine that can alter circulating catecholamine concentrations in some [ 4 , 42 ] but not all [ 3 , 5 , 8 , 28 ] studies so is a confounding variable. Consumption of EGCG via capsule form generates an average peak plasma concentration C max 2.

Although it has long been recognised that flavanoids inhibit COMT activity [ 29 ], only more recently has EGCG been shown to inhibit human hepatic cytosolic COMT activity in vitro [ 27 , 44 ]. Inhibition of COMT could allow for sustained if not elevated plasma catecholamine concentrations and potentially reduce production of downstream catecholamine metabolites metanephrine and normetanephrine.

The results of our study throw into question this mechanism. As stated above, plasma catecholamines were greatly reduced after EGCG supplementation and we found no differences in the resting or exercise-induced increases in plasma metanephrine or normetanephrine compared to the placebo trial suggestive of similar COMT activity in each trial.

Thus, the mechanism s by which plasma circulating catecholamines are lower during exercise following EGCG supplementation are unclear. EGCG as opposed to green tea extract has been shown to have no influence α-adrenergic stimulation of rat vascular and aortic tissue in vitro [ 45 ].

Adding to the complexity of responses, administration of caffeine to rats with or without EGCG reduced the increase in catecholamines and vascular responses associated with caffeine administration alone [ 47 ]. As an alternative suggestion to explain our data, EGCG has been shown to inhibit DOPA decarboxylase, slowing conversion of l -DOPA into dopamine; the upstream product of NA and AD within adrenal medulla chromaffin cells and sympathetic neuron [ 48 ].

However, further investigation is warranted to detail the exact in vivo mechanistic pathways involved during exercise in man. In conclusion, this study explored the impact of acute ingestion of the polyphenol epigallocatechin gallate EGCG on catecholamine, catecholamine metanephrines, systemic metabolic and cardio-vascular variables across a range of exercise intensities during graded cycle exercise in man.

Circulating catecholamine concentrations and peak lipid oxidation were lower in response to a graded exercise test following acute EGCG supplementation. Study limitations: Blood samples collected at the end of each stage were able to be analysed for catecholamines and catecholamine metabolites; however, we established five metabolic time points which were examined to remove potential bias and mitigated this limitation, all samples were however analysed for plasma blood lactate and plasma blood glucose.

Second, the lack of a post ingestion respiration sample, in any future study it would be beneficial to add this sample point to allow a more complete picture of any subtle changes which may have occurred during the rest period.

The data that support the findings of this study are not openly available due to reasons of sensitivity i. human data and are available from the corresponding author upon reasonable request from a controlled access repository.

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Biol Trace Elem Res 3 — Article CAS PubMed PubMed Central Google Scholar. Brown A, Lane J, Holyoak C, Nicol B, Mayes AE, Dadd T Health effects of green tea catechins in overweight and obese men: a randomised controlled cross-over trial.

Br J Nutr 12 — Achten J, Jeukendrup AE Optimizing fat oxidation through exercise and diet. Nutrition 20 7—8 — Vukovich MD, Costill DL, Hickey MS, Trappe SW, Cole KJ, Fink WJ Effect of fat emulsion infusion and fat feeding on muscle glycogen utilization during cycle exercise.

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Nutrition 32 3 — Venables MC, Hulston CJ, Cox HR, Jeukendrup AE Green tea extract ingestion, fat oxidation, and glucose tolerance in healthy humans. Am J Clin Nutr 87 3 — Roberts JD, Roberts MG, Tarpey MD, Weekes JC, Thomas CH The effect of a decaffeinated green tea extract formula on fat oxidation, body composition and exercise performance.

J Int Soc Sports Nutr 12 1 Dean S, Braakhuis A, Paton C The effects of EGCG on fat oxidation and endurance performance in male cyclists. Int J Sport Nutr Exerc Metab 19 6 — Eichenberger P, Mettler S, Arnold M, Colombani PC No effects of three-week consumption of a green tea extract on time trial performance in endurance-trained men.

Exfrcise Scholarly Community. Entry Journal Book Video Image About Entry Coconut Oil for Health Video Exegcise. Submitted Successfully! Thank you for your contribution! You can also upload a video entry or images related to this topic. Version Summary Created by Modification Content Size Created at Operation 1 Hadi Nobari. EGCG and exercise performance

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TOP 5 Weight Loss Supplements (Stop Wasting Your Money) Click name to view affiliation. Green-tea extract epigallocatechingallate; EGCG Flavored olive oil been shown to performacne endurance capacity in mice. Natural alternatives to diabetes medications a green-tea extract can edercise EGCG and exercise performance performancr EGCG and exercise performance as a result spare glycogen stores, then athletes may benefit through improved endurance performance. Eight male cyclists completed a study incorporating a 3-way crossover, randomized, placebo-controlled, double-blinded, diet-controlled research design. The study found little benefit in consuming green-tea extract on fat oxidation or cycling performance, unlike caffeine, which did benefit cycling performance. Therefore, it was concluded that green-tea extract offers no additional benefit to cyclists over and above those achieved by using caffeine. Paton is with the Eastern Institute of Technology, Hawkes Bay, New Zealand.

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