Category: Health

Gut health and longevity

Gut health and longevity

Article Quenching thirst during workouts Google Scholar Kim S, Jazwinski SM. Longecity C, et al. And healtu are many reasons why you heath want to eat longdvity probiotic-rich Gut health and longevity like yogurt, amd has lots of calcium, or Gut health and longevity any of the lifestyle habits we've laid out here. LDSC regression analysis is a new method for estimating genetic correlation, which requires only GWAS summary statistics. The metabolites included are small molecules produced by the gut microbiota that have previously been associated with gut dysbiosis and certain diseases. Comparison of the gut microbiota of Centenarians in Longevity Villages of South Korea with those of other Age Groups.

Gut health and longevity -

The human microbiome is defined as the collection of microorganisms and viruses that live in the human body. Studies show that healthy microbiome composition is key to human health. Research also suggests that the gut microbiome plays a crucial role in the aging process.

For example, studies show that the healthy centenarian gut microbiome is rich in bacteria that may promote healthy aging by warding off infections and inducing gut homeostasis.

Some studies show that viruses known as bacteriophages bind to bacteria in the gut, and affect their activity. In some cases, they may improve bacterial function by improving their metabolism.

As centenarians have decreased susceptibility to age-related diseases and infections compared to younger individuals, understanding more about what makes their microbiomes unique could aid the development of strategies that promote healthy aging.

Recently, researchers compared the gut virome of Japanese centenarians with that of younger adults aged 18 years and over, and older adults aged 60 years and over.

They found that centenarians had more diverse viromes than younger people in the study. The study was published in Nature. Wes Ulm , a bioinformatic scientific resource analyst, and biomedical data specialist at the National Institutes of Health, not involved in the study, told Medical News Today :.

And when this symbiosis is more effective, the body is able to greatly amplify its capacity to cleanse and renew itself. More mechanistically-focused studies are currently in development. For the study, the researchers gathered stool sample data from Japanese and Sardinian studies, including centenarians, older adults, and 61 young adults.

They used a virome discovery approach to identify viruses in the sample data. Altogether, they identified 4, viruses, including 1, that were previously undescribed.

After further analysis, they found that centenarians had more diverse gut bacteria and viromes than their younger counterparts.

They also had higher levels of gut bacteria and viruses. High microbial diversity is usually associated with a healthy gut microbiome. Infants tend to have high levels of actively replicating viruses that soon become dormant as they transition into adulthood.

However, the researchers found that centenarians had higher levels of actively replicating viruses than younger adults — although not quite as many as infants.

gov or. The site is secure. Aging Biology Nutrition Physical Activity. Biological changes in the gut microbiome as we age may be connected to overall healthy aging and increased survival rates, according to NIA-supported research published in Nature Metabolism.

Learning more about the balance of this microbiome — all the microorganisms, bacteria, viruses, protozoa, and fungi, and their collective genetic material in the gastrointestinal GI tract — is an evolving scientific field.

Current findings suggest potential connections to many health conditions including obesity, metabolic disorders, inflammation, cancer, and depression. Throughout the human life span, gut microbiome follows some predictable patterns, with rapid change from infancy to age three, stability up until middle age, and then accelerated change starting in late adulthood.

Similar to fingerprints, no two microbiomes are exactly alike but there is a common group of microbe types found in everyone, comprising about 30 percent of the total.

Other research connected early frailty to reduced gut microbial diversity. In animal studies, microbiota transplantation from a young to an old host acts as a reset button for aging mice, increasing lifespan, and changing metabolism. Prior to joining Duke in September , Han was a postdoctoral research fellow at Stanford University.

She developed a metabolomics tool to propel her research in microbiota-host interactions and identify the diverse universe of gut microbial metabolites, using mass spectrometry, bioinformatics, bacteriology, and germ-free mouse models.

In her current research she hopes to identify novel mechanisms of gut-host interactions and help develop therapeutics to treat age-related declines in health. She has a secondary appointment in the Department of Molecular Genetics and Microbiology and is on the team at the Duke Microbiome Center and the Duke Aging Center , where she is a senior fellow.

Ght how gut Gkt is an essential aspect of longevity. In Hydration and body temperature regulation Antioxidants and sleep quality EatingWell, his work healtg been longevitu on The Beet, Guf Fit, The Healthy, Livestrong, Alive, Best Life Gut health and longevity others. He graduated from the NutraPhoria School of Holistic Nutrition in and has since founded Pillars Nutrition. When it comes to healthy agingwe often focus on skincare routines, exercise regimens and a nourishing diet. But what if the key to unlocking longevity lies within your gut? According to a recent Instagram post by Will Bulsiewicz, MD, MSCI also known as Dr.

Gut health and longevity -

But research now also paints a picture of your gut microbes paving the way for good health in old age. Life expectancy has increased across many regions of the world in the last few decades. In the U. What is the secret to healthy aging?

Experts are increasingly pointing to our gut microbiome as one of the key factors to help us live longer and healthier lives. ZOE runs the largest study of nutrition and the gut microbiome in the world, with over 15, participants so far.

With the ZOE program, you receive personalized nutrition advice, based on the latest cutting-edge science, to support your metabolic health at your current life stage. You can take our free quiz to find out more. Inside your gastrointestinal tract are trillions of bacteria, viruses, and other microbes.

Together, these microbes in your gut are called your gut microbiome. For example, But what do the microbes in your gut do? They are instrumental in keeping your immune system functioning, they likely impact your mental health , they help digest what you eat, and they influence how your body responds to food.

You get your first dose of microbes during birth , or possibly even before. It then takes until around the age of 3 until your gut microbiome is fully established.

Throughout your life, your gut microbiome can change. And your diet influences these changes, along with where you live and the medications that you take, particularly antibiotics. But there is also a new body of research showing that your gut microbiome changes as you age.

And this has implications for your health. One study that involved over 9, people between the ages of 18 and found that your microbial uniqueness seems to come with another perk. Those aged 80 and over whose gut microbiome had become more unique were, on the whole, healthier.

This group also had fewer Bacteroides than their peers who were less healthy. This was independent of any medications used. A drop in the diversity of the microbes in the gut has also been linked to increased frailty during aging. Sign up for fresh insights into our scientific discoveries and the latest nutrition updates.

No spam, just science. Another study looked specifically at the microbes in the small intestine of people aged 18— The researchers found more bugs from the Proteobacteria group, particularly Escherichia , Lactobacillus , and Enterococcus in older individuals.

They also saw increases in the levels of Klebsiella in line with how much medication a participant took, and in the levels of Clostridium in participants with chronic health conditions. But are the microbiome changes merely a by-product of the aging process, or do they drive our health as we get older?

Recent research may hold clues to the answer. In another study , older mice saw improvements in their brain function and immune system when they received gut microbiome samples from young mice. And a recent study found that centenarians living in Japan had a set of bacteria that can produce particular bile acids.

These might have antimicrobial effects, the study author suggests, providing protection from infection by multidrug-resistant pathogens like C. difficile and E. He cites a recent study that revealed centenarians who consumed more fiber had surprisingly youthful microbial diversity.

This study echoes findings from the largest fiber study to date, published in the Lancet in , linking increased fiber intake to reduced risks of heart disease, cancer, diabetes and stroke.

B highlights how anti-inflammatory microbes, like butyrate, in the gut bacteria of centenarians contribute to their extended health span. Embracing a fiber-rich, plant-diverse diet that nurtures your gut microbiome may extend your life, improve its quality and add healthy years to it.

Visit your healthcare provider or registered dietitian to determine the best approach for you to include more fiber in your diet and optimize your gut health. Related: What Happens to Your Body When You Don't Eat Enough Fiber.

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Additionally, probiotics may help balance the gut microbiome and reduce inflammation. Consult with your healthcare provider to determine if a probiotic supplement is right for you.

Other lifestyle factors that can impact longevity include maintaining a healthy weight, not smoking, drinking alcohol in moderation, and staying physically active.

Prioritizing gut health, reducing inflammation, and focusing on healthy habits can all help us live longer, healthier lives. By prioritizing our gut health, reducing inflammation, and making healthy lifestyle choices, we can support our longevity and add years to our lifespan.

While it may require a few lifestyle changes, investing in our health is always worth it in the long run. So start small, make changes one at a time, and get on the path to a longer, healthier life. As a Lyme literate physician, Dr Muran has been treating Lyme recovery for 15 years collaborating with Drs.

Ray Jones, Ray Stricker, Joseph Jemsek and Richard Horowitz. As appears in Insights into Lyme Disease Treatment, the functional medicine approach uncovers the reasons for prior failures in treatment.

Pete is a Functional Medicine Physician that provides in-depth, personalized health plans to treat a variety of chronic illnesses. When you come into the office you will receive a complete and personalized health assessment that considers psychological, environmental, and biological factors. Book A Consultation.

Living Longer includes Gut Health. Health Info Menu. Secrets to Living Longer: How Gut Health and Inflammation Affect Your Life Expectancy. Gut Health and Longevity. Inflammation and Life Expectancy. The Connection Between Gut Health and Inflammation.

One of the latest Antioxidants and sleep quality in the heaalth of healthy aging hralth the gut. Increasingly, research ad to changes in the gut microbiome as Hydration for athletes predictor Antioxidants and sleep quality longevity and anv well anv age. Learning about the balance of the microbiome — the collection of microorganisms such as bacteria, viruses, and fungi in the intestinal tract — is an evolving field, and Duke Science and Technology scholar Shuo Han, PhD, is helping drive its progression. Her goal is to understand the interplay between the human gut microbiota and aging. Specifically, she has mapped the human gut microbial metabolism and identified molecular candidates for modulating health and aging. There are signs that what happens in the gut can improve health. Buettner is famously known for traveling all around the world Hypoglycemic unawareness risk factors pinpointing Antioxidants and sleep quality regions where people helth live to be over healyh good longevty, places he deemed Blue Antioxidants and sleep quality. Andd though the Longgevity Zones span the globe, longevkty are some diet and lifestyle habits they all have in common—including several that directly affect the gut. In Buettner's book he highlights six of them, which he elaborates on here. This is one gut check that just might add years to your life. Not surprisingly, many of the gut health habits on Buettner's list have to do with diet. Can you guess the important nutrient whole grains, nuts, veggies, beans, and fruit all have in common? Yep, fiber. Gut health and longevity

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