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How much cayenne pepper per day is healthy? Capsaicin in hot peppers Cayenne pepper health supplements their infamous burning sensation. As pdpper supplement or in topical healfh, it may supplemments promote weight loss, reduce inflammation, and relieve pain. Most people recognize capsaicin as Cayenne pepper health supplements substance responsible Cayenne pepper health supplements the burning sensation when you eat hot peppers. This article explains everything you need to know about capsaicin supplements, including their benefits, dosage, and side effects. When consumed, foods containing this substance stimulate pain receptors in your tongue, causing the sensation of heat that most people experience 12. Some people are more sensitive to capsaicin than others, which is usually related to how often they eat spicy foods. Your tongue adjusts to the sensation over time 3.