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Inflammation and fertility

Inflammation and fertility

Maintaining a healthy body weight efrtility believed to help reduce oxidative stress. Expert Pitch Inflammation and fertility Query Expert Directory. Female infertility. Inflammation and fertility

Inflammation and fertility -

Upon entry into their respective studies, each participant completed a detailed dietary questionnaire which was used to calculate adherence to each dietary pattern. Overall, higher adherence to all dietary patterns was associated with an increased chance of becoming pregnant.

The diet pattern, however, with the most consistent and strongest effect on improving time to conceive was the DII, a dietary pattern designed to minimize inflammation in the body.

In both studies, women who followed a more anti-inflammatory diet had a greater chance of becoming pregnant compared to those who ate a less anti-inflammatory diet.

The results were even stronger in women with obesity and in women 35 years and older. Inflammation has been shown to play an important role in the development of insulin resistance, a condition that can influence hormonal function and interfere with ovulation.

Keep in mind these findings may not apply to the general population since the study participants tended to eat a healthier diet, were less likely to smoke and had higher education and income levels.

The DII is a scoring system based on 45 inflammation-promoting and anti-inflammatory food components. The top anti-inflammatory contributors to the DII score include fibre, magnesium, beta-carotene, vitamins A, B, C, D and E and polyunsaturated fat — the type of fat found in foods such as oily fish, flax and chia seeds, walnuts, sunflower oil and grapeseed oil.

Although the other dietary patterns studied also have anti-inflammatory components, the DII is unique in that it focuses on how strongly each component affects inflammatory proteins in the bloodstream. The DII is also the only diet scoring system that includes specific vitamins and minerals.

While these micronutrients were included in the DII for their anti-inflammatory potential, they may also enhance fertility in other important ways. Eating a healthy diet has also been shown to increase the likelihood of successful pregnancy among women undergoing assisted reproductive technologies ART.

The pro-fertility diet, developed by Harvard University researchers, is based on foods and nutrients tied to positive ART outcomes in past studies. Mounting evidence suggests that optimizing nutrition and diet is important for increasing fertility potential among women trying to conceive naturally and among those using ART.

Eating a healthy diet is also linked to improved fertility in men. Leslie Beck, a Toronto-based private practice dietitian, is director of food and nutrition at Medcan. Follow her on Twitter LeslieBeckRD.

antioxidants , they can cause considerable damage to DNA and cell membranes, leading to cell death. Mitochondria, a little organelle that sits within most cells, is the main source of reactive oxygen species. As oxygen is broken down metabolised to produce energy, electrons can escape from the energy production chain and these transform oxygen from a stable molecule to one that loses some electrons to become unstable.

If your mitochondria are not functioning properly this will generate considerably more reactive oxygen species more on mitochondria later , leading to greater oxidative stress.

While most reactive oxygen species are produced from processes in the body, they can also come from outside sources including smoke, pollutants, tobacco, certain drugs and radiation.

Elevated levels of inflammation and oxidative stress negatively affect sperm and egg quality, reducing fertilisation and conception rate. Detecting low-grade inflammation and oxidative stress are not routine procedures in fertility pathology so often the only sign of these underlying conditions may be poor egg quality, poor fertilisation rates, recurrent implantation failure or miscarriage.

PCOS: Women with PCOS show chronic low-grade inflammation, characterised by increased plasma levels of inflammatory cytokines, which have been associated with insulin resistance.

Levels of oxidative stress are also increased in PCOS. Circulating levels of antioxidants, which are our defence against oxidative stress, are also lower. Endometriosis: Endometriosis is an oestrogen driven inflammatory condition. Male Factor: Increase in circulating markers of inflammation and oxidative stress are seen in male factor infertility.

They lead to DNA fragmentation which is a key contributor to poor fertilisation rates, low rates of blastocyst formation and recurrent early pregnancy loss. The good news is that adopting strategies to dampen chronic inflammation and oxidative stress are very effective in enhancing fertility and increasing pregnancy success.

Diet is among the most easily controlled factors that can manipulate the gut microbiota and influence inflammation. Modulators of inflammation include Vitamin D and omega-3 fatty acids but key is prebiotic dietary fibre. Make sure you are getting lots of wholegrains in your day and fresh fruits and vegetables that are packed with natural prebiotics - just like Fertile Gut!

Jerusalem artichokes, chicory, garlic, onion, leek, shallots, spring onion, asparagus, beetroot, fennel bulb, green peas, snow peas, sweetcorn, savoy cabbage, custard apples, nectarines, white peaches, persimmon, tamarillo, barley and rye bread.

A scoop of Fertile Gut in a berry smoothie is also a great way to pack in proven prebiotic fibre, antioxidants and polyphenols.

A great start to any day! Hi, I'm Dr Cecilia Kitic founder of Fertile Gut. We can't wait to help support you on your journey to improving your gut health! Having spent over 20 years researching in the areas of immunonutrition, physiology, biochemistry and gut health we now get to translate science into practice, sooner.

Our gut microbiome provides a foundation for our immune system, metabolism, brain and heart health, and hormone balance. At the Zita West Clinic we do specialist blood tests to see if this is the case or not.

It is also extremely important to reduce the effect of stress, which can impact the immune system, and we use other, holistic treatments — such as acupuncture and hypnotherapy — to help with that. There are certain foods that are inflammatory and others that help reduce inflammation in the body.

Try to increase the following in your diet, because these foods are anti-inflammatory:. In addition, try to eat more white fish, beans and pulses as your main protein sources, rather than poultry and red meat.

Although turkey and chicken are fine in moderation, in general animal protein is considered more inflammatory for the body than fish and plant protein.

You may wish to limit your intake of red meat and dairy products, as they contain arachidonic acid, which the body can use to make inflammatory eicosanoids. Unsurprisingly, the pro-inflammatory foods in our diet comprise refined carbohydrates and sugars, excess saturated fats, processed foods, junk foods and hydrogenised or partially hydrogenised fats.

Avoid them as often as you can. Caffeine and alcohol are pro-inflammatory, too. Finally, avoid stress. For a detailed nutrition consultation tailored for you either in the clinic or by phone, contact us here. Get in touch with one of our dedicated IVF advisers for more information on this, and how we can help you conceive.

At Zita West Clinic, we understand that each individual person needs an individual approach to starting a family. From the moment you walk through our door, you will receive personalised and comprehensive guidance and advice to help you through your fertility journey: the future of your family starts here.

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