Alpha-lipoic acid side effects -
When considering the use of herbal supplements, seek the advice of your doctor. If you choose to use alpha-lipoic acid, use it as directed on the package or as directed by your doctor, pharmacist, or other healthcare provider. Do not use more of this product than is recommended on the label.
Call your doctor if the condition you are treating with alpha-lipoic acid does not improve, or if it gets worse while using this product. Do not use different forms tablets and capsules of alpha-lipoic acid at the same time without medical advice.
Using different formulations together increases the risk of an overdose. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra alpha-lipoic acid to make up the missed dose.
This includes devil's claw, fenugreek, garlic, guar gum, horse chestnut, Panax ginseng, psyllium, and Siberian ginseng. Get emergency medical help if you have signs of an allergic reaction : hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Although not all side effects are known, alpha-lipoic acid is thought to be possibly safe when taken as directed. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
You may report side effects to FDA at FDA Do not take alpha-lipoic acid without medical advice if you are using any of the following medications:. This list is not complete. Other drugs may interact with alpha-lipoic acid, including prescription and over-the-counter medicines, vitamins, and herbal products.
Not all possible interactions are listed in this product guide. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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Special Enrollment See all topics Looking for Medicare coverage? Humans make a small amount of ALA on their own, although the concentration in our bloodstreams goes up substantially when we eat a healthy diet. Alpha lipoic acid also called lipoic acid or thioctic acid is an organosulfur compound found in the body and also synthesized by plants and animals.
Even though we can make some of it on our own without supplements or outside food sources, eating an antioxidant-packed diet plus potentially using ALA supplements can increase the amount circulating in the body.
Studies show this can have far-reaching benefits. Within our cells, ALA is converted into dihydrolipoic acid, which has protective effects over normal cellular reactions, such as those involved in metabolic functions and neuron signaling.
Like other antioxidants, alpha lipoic acid can help slow down cellular damage that is one of the root causes of diseases. It also works in the body to restore essential vitamin levels, such as vitamin E and vitamin C, and acts as a cofactor for several important mitochondrial enzymes.
Additionally, it helps the body digest and utilize carbohydrate molecules. Note: Alpha lipoic acid is not the same thing as alpha linolenic acid , a type of omega-3 fatty acid.
Because it acts like an antidote to oxidative stress and inflammation, alpha lipoic acid seems to fight damage done to the blood vessels, brain, neurons and organs, like the heart or liver. Being low in antioxidants in general can speed up in the aging process, resulting in symptoms like a weakened immune function, decreased muscle mass, cardiovascular problems and memory problems.
Finally, alpha lipoic acid can increase how the body uses a very important antioxidant known as glutathione. Alpha lipoic acid can protect cells and neurons involved in hormone production, offering protection against type 2 diabetes.
Alpha lipoic acid supplementation seems to help improve insulin sensitivity and might also offer protection against metabolic syndrome — a term given to a cluster of conditions like high blood pressure, cholesterol and body weight.
Some evidence also shows that it can help lower blood sugar levels. A systematic review and meta-analysis, along with a controlled clinical trial, showed that ALA is an effective drug in the treatment of diabetic neuropathy, which affects about 50 percent of people with diabetes.
Diabetic neuropathy nerve damage causes symptoms like tingling, numbness and burning in the limbs. About — milligrams per day in IV form has been shown to be beneficial.
ALA is used to help relieve other complications and symptoms of type 2 diabetes too, such as cardiovascular problems, eye-related disorders, pain and swelling.
Most studies show that high doses of ALA in IV form are more effective than eating ALA-rich foods. According to a randomized, double-blind, placebo-controlled clinical trial, ALA also offers help in managing idiopathic pain pain of unknown origin in people without diabetes.
A major benefit of alpha lipoic supplementation in diabetics is the lowered risk for neuropathic complications that affect the heart, since around 25 percent of people with diabetes develop cardiovascular autonomic neuropathy CAN.
CAN is characterized by reduced heart rate variability and is associated with an increased risk of mortality in people with diabetes.
Oxidative stress can damage nerves in the eyes and cause vision problems, especially in people with diabetes or older adults. Results from certain studies demonstrate that long-term use of ALA can halt oxidative damage that can result in modified DNA in the retina.
Some health care professionals use alpha lipoic acid supplements to further help prevent their patients from experiencing neuron damage, memory loss, motor impairment and changes in cognitive functioning due to its antioxidant activity.
ALA seems to easily make its way into the brain by passing the blood-brain barrier, where it can protect delicate brain and nerve tissue.
In adults, alpha lipoic acid supplementation also seems to positively impact patients with immune deficiency syndromes and serious viruses. It does this by restoring blood total glutathione levels and improving functional reactivity of lymphocytes to T-cell mitogens. These are cells in the immune system that fight pathogens.
When it comes to battling physical signs of aging on the skin, certain studies have found that topical treatment creams containing 5 percent alpha lipoic acid can help reduce fine lines caused by exposure to sun ways.
ALA is thought to act as an anti-aging substance because it helps restore skin tissues and epidermal structure while battling free radicals. Due to its ability to help convert foods into nutrients, ALA may help increase energy metabolism, which is why some athletes use ALA supplements for enhanced physical performance.
A meta-analysis of placebo-controlled trials also found that ALA treatment significantly reduced BMI and body weight and may protect against obesity. What are the side effects of taking alpha lipoic acid?
Side effects of ALA in supplement form are generally rare, but for some people they can include :. The best way to get any nutrients is ideally through real food sources, since this is how your body knows how to absorb and use various chemicals best.
That being said, when you eat a whole food-based diet and vary the types of things you eat, chances are you consume a decent amount in addition to what your body already makes on its own. Taking oral ALA supplements with a meal is believed to decrease its bioavailability, so most experts recommend taking it on an empty stomach or at least one hour before or after for the best results.
Alpha-lipoic acid ALA is a naturally-occurring fatty acid. Your body makes its own Al;ha-lipoic, but it Nutrient-rich botanicals also Alpha-lipoic acid side effects in effecfs foods sidr as Protective against carcinogens Alpha-lipiic. ALA supplements may provide health benefits, such as aiding in weight loss and managing blood sugar, but more research needs to be done to support its use. This article reviews the potential uses of ALA and also covers side effects and possible interactions. Supplement use should be individualized and vetted by a healthcare provider. No supplement is intended to treat, cure, or prevent disease. Alpha-lipoic effeects ALA is L-carnitine and fertility found in Allha-lipoic body and is important in converting food into energy. It is xide fatty Alph-lipoic that converts glucose or blood Protective against carcinogens into energy through the aid of oxygen. When oxygen is used, the process of converting sugar into energy is called aerobic metabolism. They have biological activities that act to influence cell and tissue metabolism, function, and responsiveness to hormonal and other signals. Join us to uncover the benefits, potential side effects, recommended dosages, and much more about this exceptional compound.
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