Resveratrol for weight loss -
We hypothesized that gut microbiota may be a potential target for resveratrol and quercetin to prevent the development of obesity.
The aim of this research was to confirm whether a combination of quercetin and resveratrol CQR could restore the gut microbiota dysbiosis induced by a high-fat diet HFD.
In this study, Wistar rats were divided into three groups: a normal diet ND group, a HFD group and a CQR group. The CQR group was treated with a HFD and administered with a combination of quercetin [30 mg per kg body weight BW per day] and resveratrol [15 mg per kg body weight BW per day] by oral gavage.
At the end of 10 weeks, CQR reduced the body weight gain and visceral epididymal, perirenal adipose tissue weight. Moreover, CQR also reduced serum lipids, attenuated serum inflammatory markers [interleukin IL -6, tumor necrosis factor TNF -α, monocyte chemotactic protein MCP -1] and reversed serum biochemical parameters adiponectin, insulin, leptin, etc.
Importantly, our results demonstrated that CQR could modulate the gut microbiota composition. Overall, these results indicated that administration of CQR may have beneficial effects on ameliorating HFD-induced obesity and reducing HFD-induced gut microbiota dysbiosis.
Zhao, Q. Zhang, W. Ma, F. Tian, H. Shen and M. Zhou, Food Funct. To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.
If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given. If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given.
Read more about how to correctly acknowledge RSC content. Fetching data from CrossRef. On the other, it is known that resveratrol has hypolipemiant properties, but its effect on the use of accumulated fat has not been extensively analysed. This thesis shows, on the one hand, the results obtained after treatment with CLA in hamsters subjected to energy restriction and, on the other, the effect of resveratrol on accumulated fat and lipolytic activity in cell cultures of adipocytes of murinae and humans.
The results obtained show that CLA does not foment weight or body fat loss, induced by an energy restriction diet. Neither does it induce greater lipolysis, nor improvement in serum parameters, in glucose homeostasis or insulin function to any greater extent than with the slimming diet itself.
On the contrary, resveratrol reduces the accumulation of triglycerides, in part by activation of lipolysis, in both the adipocytes of mice and of humans. For all these reasons, it can be concluded that, while CLA may not be a molecule useful in treating obesity, when resveratrol is included in hypocaloric diet, it could well be a useful tool for reducing body fat.
More studies are required regarding this latter molecule, firstly to describe other effects of resveratrol and its activating mechanisms, as well as the possible adverse effects and toxicity; secondly studies amongst humans confirm the previously observed effects.
Materials provided by Basque Research. Note: Content may be edited for style and length. Science News. Facebook Twitter Pinterest LinkedIN Email. FULL STORY. Fat reduction with functional ingredients Conjugated Linoleic Acid CLA and resveratrol are two functional ingredients that, in various experiments on living beings and in vitro, have proved to have a fat-reducing effect.
RELATED TERMS Grape Bone marrow Red Wolf Saturated fat Mediterranean diet Adipose tissue Black widow spider Color vision. Story Source: Materials provided by Basque Research. Cite This Page : MLA APA Chicago Basque Research. ScienceDaily, 18 March Basque Research.
Resveratrol may be useful tool for reducing body fat. This antioxidant compound can be found naturally in red wine, red grape skins, purple grape juice, mulberries, and in smaller amounts in peanuts, and has been used as a way to enhance an already healthy lifestyle.
Much of the initial excitement about resveratrol began in Its potential to protect the cardiovascular system, prevent cancer, and expand lifespan, among others, has been gaining interest ever since, says John M.
Pezzuto, Ph. Today, resveratrol supplements are being promoted as a way to boost energy, maintain body weight, and increase muscle endurance. But how effective—and safe—is it, really?
Among the ongoing medical explorations, one of resveratrol's most immediate possibilities lies in the realm of fitness. Resveratrol is a source of high hopes, though much about it remains unknown.
Yes, there is a plethora of research on the resveratrol-weight loss connection, but most of it is on animals. What these studies have shown, however, is encouraging: Resveratrol appears to activate enzymes that help muscles use oxygen more efficiently, a performance enhancement known to runners as higher VO2 max.
In simplified terms, the higher your VO2 max, the lengthier and more intense the workout you can handle. Fitness experts started to take notice of resveratrol in , when the journal Cell reported that mice given the antioxidant ran nearly twice as far on a treadmill as unsupplemented critters.
The treatment "significantly increases the animal's resistance to muscle fatigue," researchers concluded. Translation: More energy and less muscle exhaustion led to a better workout. The hypothesis? Resveratrol stimulates enzymes called sirtuins, which control important functions throughout the body, including DNA repair, cell life, aging, and fat production.
Sure enough, mice on resveratrol had bigger, denser mitochondria, so their charged muscles were better able to use oxygen. In theory, this means that resveratrol may be able to help you work out longer or harder or both before your muscles become too fatigued to perform.
These more intense workouts will then condition muscles for an even greater effort the next time you lace up, for a continuous cycle of improved fitness. Good news: HIIT, cardio, and strength training all have mitochondrial benefits , too. Again, research outside the laboratory has been limited: In one of the few completed human trials, 90 sedentary men and women were given a resveratrol-based cocktail or placebo daily for 12 weeks.
After three months, everyone jumped on treadmills. What's more, they also had significantly lower heart rates during exercise—the equivalent of the results of three months' light to moderate training—apparently just from taking the daily supplement.
For all the evidence about resveratrol's exercise benefits, manufacturers' claims that the supplement helps people lose or maintain weight are harder to substantiate. Some proponents say the resveratrol-weight loss link works in part by interacting with blood sugar. This means that more calories go into muscles and fewer go into fat cells," says Smoliga.
Indeed, research presented at a conference of the Endocrine Society showed that in the laboratory, resveratrol inhibited the production of mature fat cells and hindered fat storage—at least at the cellular level.
In addition, a study found that mice fed a high-fat diet with resveratrol weighed almost the same as those served a non-high-fat diet without the supplement. But because, for some, resveratrol appears to increase the ability to exercise more frequently and intensely, it's hard to pin down the real source of weight maintenance.
Other hypotheses include that resveratrol could function as an "energy restriction mimetic," meaning consuming resveratrol would be equivalent to going on a diet and reducing caloric intake, says Pezzuto. In a study , mice were fed a high-fat diet to become obese, then either exercised alone or exercised with resveratrol supplementation.
Obesity is a very common Realistic body image in developed countries, there being more Amino acid synthesis pathway in humans 1, million overweight persons currently in the world, of which more than wight suffer weigght obesity. Revseratrol illness brings with Amino acid synthesis pathway in humans other, associated conditions that result in wsight significant increase weigut the morbi-mortality Resvertrol these Rdsveratrol. Current Resveratrol for weight loss for los treatment Anti-inflammatory sleep tips various and one field of great interest is what is known as functional ingredients. These are compounds that appear in certain foods and that enhance specific corporal functions, promoting health and reducing risk of diseases. Conjugated Linoleic Acid CLA and resveratrol are two functional ingredients that, in various experiments on living beings and in vitro, have proved to have a fat-reducing effect. On the one hand, the properties attributed to CLA indicate that it prevents weight gain and the accumulation of body fat, through inhibiting the synthesis of fat and increasing the oxidation of fatty acids. However, its effects when applied in a hypocaloric diet — for the treatment of obesity — are unknown. Excessive Resveratrol for weight loss adipose tissue Cardiac arrhythmia prevention accumulation due to wwight Resveratrol for weight loss between caloric Resverattrol and energy Metabolic support complex EE characterizes obesity. However, brown adipose tissue BAT is highly specialized foor the dissipation of weught. Recent evidence indicated that olss activation of BAT and the seight of WAT browning might be promising approaches to combat obesity by increasing EE and regulating glucose and lipid metabolism. Resveratrol, which is a polyphenolic compound, has been widely acknowledged to have protective effects against obesity and related metabolic disorders. The induction of WAT browning has been considered as one of the crucial factors in the metabolic benefits of resveratrol. Nevertheless, the specific mechanism that is involved is largely unclear. As a prebiotic-like polyphenol, resveratrol is able to modulate the composition of gut microbiota.Resveratrol for weight loss -
Facebook Twitter Pinterest LinkedIN Email. FULL STORY. Fat reduction with functional ingredients Conjugated Linoleic Acid CLA and resveratrol are two functional ingredients that, in various experiments on living beings and in vitro, have proved to have a fat-reducing effect.
RELATED TERMS Grape Bone marrow Red Wolf Saturated fat Mediterranean diet Adipose tissue Black widow spider Color vision. Story Source: Materials provided by Basque Research. Cite This Page : MLA APA Chicago Basque Research. ScienceDaily, 18 March Basque Research. Resveratrol may be useful tool for reducing body fat.
Retrieved February 14, from www. htm accessed February 14, Explore More. Japanese Knotweed Extract Could Cut Cancer Risk of Processed Meat. The range of sausages and hams had a Hidden in the Seeds: Bacteria Found to Survive the Harsh Interior of Passion Fruit Seeds.
Compound Found in Red Wine Opens Door for New Treatments for Depression, Anxiety. July 29, A new study has revealed that the plant compound resveratrol, which is found in red wine, displays anti-stress effects by blocking the expression of an enzyme related to the control of stress in the Why Some Red Wines Taste 'Dry'.
May 8, Wine connoisseurs can easily discriminate a dry red wine, such as Cabernet Sauvignon, from a fruitier red, like Pinot Noir. Research shows resveratrol significantly reduces body weight, waist circumference, and fat mass, while increasing lean mass.
Most studies were conducted in vitro and on rats, so more evidence is necessary to conclusively establish its effectiveness in humans. Nevertheless, evidence suggests that resveratrol helps with weight loss via the following mechanisms. Note: Combine Resveratrol with our 19 practical weight loss tips for the best results.
The result is more muscle energy and less fat stored in cells. Inflammation contributes to insulin resistance, leading to increased fat storage.
Note: Learn how insulin resistance affects weight loss. This positively affects metabolism and improves metabolic disorders. A healthy metabolism means our bodies burn more calories and store less fat. By activating sirtuins, resveratrol may help muscles use oxygen more efficiently, enabling longer and more intense physical activity.
Fitness enthusiasts who take resveratrol claim it decreases muscle fatigue and gives them more energy for workouts. Note : Learn how IV therapy can help improve athletic performance. Resveratrol activates receptors in the intestinal tract that send satiety signals to the brain.
It also improves insulin sensitivity, reducing cravings, and decreases cortisol, which stimulates appetite. Research shows resveratrol helps lower body fat by inhibiting adipogenesis, the formation of fat cells, and triggering lipolysis, the process of burning fat stored in adipose tissue. Resveratrol is classified as a phytoestrogen because it is structurally similar to estrogen.
This can help build more muscle and burn more calories. Note : Learn how testosterone therapy can help you lose weight. Trans-resveratrol is the best form for weight loss because it is more prevalent and bioactive, ready to be absorbed and used in our bodies.
Cis-resveratrol is less abundant in plants and can also occur when trans-resveratrol is exposed to light. This form is less studied because of its instability. Most available studies show cis-resveratrol has weaker antioxidant, anti-inflammatory, and anti-platelet effects than the trans isomer.
Higher doses may lead to mild to moderate gastrointestinal issues. Anecdotal evidence suggests patients who take mg daily may lose 40 pounds in seven months. Van Marken Lichtenbelt WD, Vanhommerig JW, Smulders NM, Drossaerts JM, Kemerink GJ, Bouvy ND, et al.
Cold-activated brown adipose tissue in healthy men. Virtanen KA, Lidell ME, Orava J, Heglind M, Westergren R, Niemi T, et al. Functional brown adipose tissue in healthy adults. Cannon B, Nedergaard J. Brown adipose tissue: function and physiological significance.
Physiol Rev. Bargut TC, Aguila MB, Mandarim-De-Lacerda CA. Brown adipose tissue: updates in cellular and molecular biology. Tissue Cell. Penna-De-Carvalho A, Graus-Nunes F, Rabelo-Andrade J, Mandarim-De-Lacerda CA, Souza-Mello V.
Enhanced pan-peroxisome proliferator-activated receptor gene and protein expression in adipose tissue of diet-induced obese mice treated with telmisartan. Exp Physiol. Rachid TL, Penna-De-Carvalho A, Bringhenti I, Aguila MB, Mandarim-De-Lacerda CA, Souza-Mello V.
PPAR-alpha agonist elicits metabolically active brown adipocytes and weight loss in diet-induced obese mice. Cell Biochem Funct. Kim WK, Choi HR, Park SG, Ko Y, Bae KH, Lee SC. Myostatin inhibits brown adipocyte differentiation via regulation of Smad3-mediated beta-catenin stabilization.
Int J Biochem Cell Biol. Castro E, Silva TEO, Festuccia WT. Critical review of beige adipocyte thermogenic activation and contribution to whole-body energy expenditure.
Gao Z, Daquinag AC, Su F, Snyder B, Kolonin MG. Kaisanlahti A, Glumoff T. Browning of white fat: agents and implications for beige adipose tissue to type 2 diabetes. Norouzirad R, Ghanbari M, Bahadoran Z, Abdollahifar MA, Rasouli N, Ghasemi A.
Hyperoxia improves carbohydrate metabolism by browning of white adipocytes in obese type 2 diabetic rats.
Life Sci. Pardo R, Blasco N, Vila M, Beiroa D, Nogueiras R, Canas X, et al. EndoG knockout mice show increased brown adipocyte recruitment in white adipose tissue and improved glucose homeostasis. Guan L, Gong D, Yang S, Shen N, Zhang S, Li Y, et al. Genipin ameliorates diet-induced obesity via promoting lipid mobilization and browning of white adipose tissue in rats.
Phytother Res. Wang S, Wang X, Ye Z, Xu C, Zhang M, Ruan B, et al. Curcumin promotes browning of white adipose tissue in a norepinephrine-dependent way. Hu J, Christian M. Hormonal factors in the control of the browning of white adipose tissue.
Merlin J, Sato M, Chia LY, Fahey R, Pakzad M, Nowell CJ, et al. Rosiglitazone and a beta3-adrenoceptor agonist are both required for functional browning of white adipocytes in culture.
Front Endocrinol. Sepa-Kishi DM, Ceddia RB. Exercise-mediated effects on white and brown adipose tissue plasticity and metabolism. Exerc Sport Sci Rev. Dempersmier J, Sambeat A, Gulyaeva O, Paul SM, Hudak CS, Raposo HF, et al. Cold-inducible Zfp activates UCP1 transcription to promote browning of white fat and development of brown fat.
Mol Cell. Gao Y, Qimuge NR, Qin J, Cai R, Li X, Chu GY, et al. Acute and chronic cold exposure differentially affects the browning of porcine white adipose tissue. Bonet ML, Mercader J, Palou A. A nutritional perspective on UCP1-dependent thermogenesis. El Hadi H, Di Vincenzo A, Vettor R, Rossato M.
Food ingredients involved in white-to-brown adipose tissue conversion and in calorie burning. Kris-Etherton PM, Hecker KD, Bonanome A, Coval SM, Binkoski AE, Hilpert KF, et al. Bioactive compounds in foods: their role in the prevention of cardiovascular disease and cancer. Am J Med.
Godoy LD, Lucas JE, Bender AJ, Romanick SS, Ferguson BS. Targeting the epigenome: screening bioactive compounds that regulate histone deacetylase activity.
Mol Nutr Food Res. Walle T. Bioavailability of resveratrol. Gambini J, Ingles M, Olaso G, Lopez-Grueso R, Bonet-Costa V, Gimeno-Mallench L, et al. Properties of resveratrol: in vitro and in vivo studies about metabolism, bioavailability, and biological effects in animal models and humans. Oxid Med Cell Longev.
Ko JH, Sethi G, Um JY, Shanmugam MK, Arfuso F, Kumar AP, et al. The role of resveratrol in cancer therapy. Int J Mol Sci.
Diaz M, Degens H, Vanhees L, Austin C, Azzawi M. The effects of resveratrol on aging vessels. Exp Gerontol. Aguirre L, Fernandez-Quintela A, Arias N, Portillo MP. Resveratrol: anti-obesity mechanisms of action.
Szkudelski T, Szkudelska K. Resveratrol and diabetes: from animal to human studies. Bonnefont-Rousselot D. Resveratrol and cardiovascular diseases. Rauf A, Imran M, Suleria HAR, Ahmad B, Peters DG, Mubarak MS. A comprehensive review of the health perspectives of resveratrol.
Food Funct. Lagouge M, Argmann C, Gerhart-Hines Z, Meziane H, Lerin C, Daussin F, et al. Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha.
Baur JA, Pearson KJ, Price NL, Jamieson HA, Lerin C, Kalra A, et al. Resveratrol improves health and survival of mice on a high-calorie diet. Kim S, Jin Y, Choi Y, Park T. Resveratrol exerts anti-obesity effects via mechanisms involving down-regulation of adipogenic and inflammatory processes in mice.
Biochem Pharmacol. Cho SJ, Jung UJ, Choi MS. Differential effects of low-dose resveratrol on adiposity and hepatic steatosis in diet-induced obese mice.
Br J Nutr. Jeon SM, Lee SA, Choi MS. Antiobesity and vasoprotective effects of resveratrol in apoE-deficient mice. J Med Food. Qiao Y, Sun J, Xia S, Tang X, Shi Y, Le G. Effects of resveratrol on gut microbiota and fat storage in a mouse model with high-fat-induced obesity.
Andrade JM, Paraiso AF, De Oliveira MV, Martins AM, Neto JF, Guimaraes AL, et al. Resveratrol attenuates hepatic steatosis in high-fat fed mice by decreasing lipogenesis and inflammation. Gu H, Li K, Li X, Yu X, Wang W, Ding L, et al. Chang CC, Lin KY, Peng KY, Day YJ, Hung LM.
Resveratrol exerts anti-obesity effects in high-fat diet obese mice and displays differential dosage effects on cytotoxicity, differentiation, and lipolysis in 3T3-L1 cells. Endocr J. Cheng K, Song Z, Zhang H, Li S, Wang C, Zhang L, et al. The therapeutic effects of resveratrol on hepatic steatosis in high-fat diet-induced obese mice by improving oxidative stress, inflammation and lipid-related gene transcriptional expression.
Med Mol Morphol. Voigt A, Ribot J, Sabater AG, Palou A, Bonet ML, Klaus S. Genes Nutr. Tauriainen E, Luostarinen M, Martonen E, Finckenberg P, Kovalainen M, Huotari A, et al. Distinct effects of calorie restriction and resveratrol on diet-induced obesity and Fatty liver formation.
J Nutr Metab. Macarulla MT, Alberdi G, Gomez S, Tueros I, Bald C, Rodriguez VM, et al. Effects of different doses of resveratrol on body fat and serum parameters in rats fed a hypercaloric diet. Alberdi G, Rodriguez VM, Miranda J, Macarulla MT, Arias N, Andres-Lacueva C, et al. Changes in white adipose tissue metabolism induced by resveratrol in rats.
Nutr Metab. Alberdi G, Rodriguez VM, Miranda J, Macarulla MT, Churruca I, Portillo MP. Thermogenesis is involved in the body-fat lowering effects of resveratrol in rats. Food Chem. Rivera L, Moron R, Zarzuelo A, Galisteo M.
Long-term resveratrol administration reduces metabolic disturbances and lowers blood pressure in obese Zucker rats. Gomez-Zorita S, Fernandez-Quintela A, Lasa A, Hijona E, Bujanda L, Portillo MP. Effects of resveratrol on obesity-related inflammation markers in adipose tissue of genetically obese rats.
Nagao K, Jinnouchi T, Kai S, Yanagita T. Effect of dietary resveratrol on the metabolic profile of nutrients in obese OLETF rats. Lipids Health Dis. Trepiana J, Gomez-Zorita S, Fernandez-Quintela A, Gonzalez M, Portillo MP. Ardid-Ruiz A, Ibars M, Mena P, Del Rio D, Muguerza B, Blade C, et al.
Arias N, Macarulla MT, Aguirre L, Milton I, Portillo MP. The combination of resveratrol and quercetin enhances the individual effects of these molecules on triacylglycerol metabolism in white adipose tissue.
Eur J Nutr. Mendes KL, De Pinho L, Andrade JM, Paraiso AF, Lula JF, Macedo SM, et al. Distinct metabolic effects of resveratrol on lipogenesis markers in mice adipose tissue treated with high-polyunsaturated fat and high-protein diets.
Mendez-Del Villar M, Gonzalez-Ortiz M, Martinez-Abundis E, Perez-Rubio KG, Lizarraga-Valdez R. Effect of resveratrol administration on metabolic syndrome, insulin sensitivity, and insulin secretion. Metab Syndr Relat Disord. Faghihzadeh F, Adibi P, Rafiei R, Hekmatdoost A.
Resveratrol supplementation improves inflammatory biomarkers in patients with nonalcoholic fatty liver disease. Nutr Res. Most J, Timmers S, Warnke I, Jocken JW, Van Boekschoten M, De Groot P, et al. Combined epigallocatechingallate and resveratrol supplementation for 12 wk increases mitochondrial capacity and fat oxidation, but not insulin sensitivity, in obese humans: a randomized controlled trial.
Am J Clin Nutr. Arzola-Paniagua MA, Garcia-Salgado Lopez ER, Calvo-Vargas CG, Guevara-Cruz M. Efficacy of an orlistat-resveratrol combination for weight loss in subjects with obesity: a randomized controlled trial. Timmers S, Konings E, Bilet L, Houtkooper RH, Van De Weijer T, Goossens GH, et al.
Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans.
Konings E, Timmers S, Boekschoten MV, Goossens GH, Jocken JW, Afman LA, et al. The effects of 30 days resveratrol supplementation on adipose tissue morphology and gene expression patterns in obese men. Poulsen MM, Vestergaard PF, Clasen BF, Radko Y, Christensen LP, Stodkilde-Jorgensen H, et al.
High-dose resveratrol supplementation in obese men: an investigator-initiated, randomized, placebo-controlled clinical trial of substrate metabolism, insulin sensitivity, and body composition.
Chachay VS, Macdonald GA, Martin JH, Whitehead JP, O'moore-Sullivan TM, Lee P, et al. Resveratrol does not benefit patients with nonalcoholic fatty liver disease. Clin Gastroenterol Hepatol. Heeboll S, Kreuzfeldt M, Hamilton-Dutoit S, Kjaer Poulsen M, Stodkilde-Jorgensen H, Moller HJ, et al.
Placebo-controlled, randomised clinical trial: high-dose resveratrol treatment for non-alcoholic fatty liver disease. Scand J Gastroenterol. Yoshino J, Conte C, Fontana L, Mittendorfer B, Imai S, Schechtman KB, et al. Resveratrol supplementation does not improve metabolic function in nonobese women with normal glucose tolerance.
Vargas-Castillo A, Fuentes-Romero R, Rodriguez-Lopez LA, Torres N, Tovar AR. Understanding the biology of thermogenic fat: is browning a new approach to the treatment of obesity? Arch Med Res. Andrade JM, Frade AC, Guimaraes JB, Freitas KM, Lopes MT, Guimaraes AL, et al.
Resveratrol increases brown adipose tissue thermogenesis markers by increasing SIRT1 and energy expenditure and decreasing fat accumulation in adipose tissue of mice fed a standard diet. Wang S, Liang X, Yang Q, Fu X, Zhu M, Rodgers BD, et al. Resveratrol enhances brown adipocyte formation and function by activating AMP-activated protein kinase AMPK alpha1 in mice fed high-fat diet.
Arias N, Pico C, Teresa Macarulla M, Oliver P, Miranda J, Palou A, et al. A combination of resveratrol and quercetin induces browning in white adipose tissue of rats fed an obesogenic diet. Qiang L, Wang L, Kon N, Zhao W, Lee S, Zhang Y, et al. Brown remodeling of white adipose tissue by SirT1-dependent deacetylation of Ppargamma.
Um JH, Park SJ, Kang H, Yang S, Foretz M, Mcburney MW, et al. AMP-activated protein kinase-deficient mice are resistant to the metabolic effects of resveratrol. Park SJ, Ahmad F, Philp A, Baar K, Williams T, Luo H, et al. Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases.
Gerard P. Gut microbiota and obesity. Cell Mol Life Sci. Morris A. Gut microbiota: link between the gut and adipose tissues. Nat Rev Endocrinol. Moreno-Navarrete JM, Serino M, Blasco-Baque V, Azalbert V, Barton RH, Cardellini M, et al. Gut microbiota interacts with markers of adipose tissue browning, insulin action and plasma acetate in morbid obesity.
Jandhyala SM, Talukdar R, Subramanyam C, Vuyyuru H, Sasikala M, Nageshwar Reddy D. Role of the normal gut microbiota. World J Gastroenterol. Zhou L, Xiao X. The role of gut microbiota in the effects of maternal obesity during pregnancy on offspring metabolism. Biosci Rep. Blandino G, Inturri R, Lazzara F, Di Rosa M, Malaguarnera L.
Impact of gut microbiota on diabetes mellitus. Diabetes Metab. Saad MJ, Santos A, Prada PO. Linking gut microbiota and inflammation to obesity and insulin resistance.
Ghazalpour A, Cespedes I, Bennett BJ, Allayee H. Expanding role of gut microbiota in lipid metabolism. Curr Opin Lipidol. Sung MM, Byrne NJ, Robertson IM, Kim TT, Samokhvalov V, Levasseur J, et al. Resveratrol improves exercise performance and skeletal muscle oxidative capacity in heart failure.
Am J Physiol Heart Circ Physiol. Chen ML, Yi L, Zhang Y, Zhou X, Ran L, Yang J, et al. Resveratrol attenuates trimethylamine-N-Oxide TMAO -induced atherosclerosis by regulating TMAO synthesis and bile acid metabolism via remodeling of the gut microbiota. Sung MM, Kim TT, Denou E, Soltys CM, Hamza SM, Byrne NJ, et al.
Improved glucose homeostasis in obese mice treated with resveratrol is associated with alterations in the gut microbiome.
Brandt N, Kotowska D, Kristensen CM, Olesen J, Lutzhoft DO, Halling JF, et al. The impact of exercise training and resveratrol supplementation on gut microbiota composition in high-fat diet fed mice. Physiol Rep. Campbell CL, Yu R, Li F, Zhou Q, Chen D, Qi C, et al.
Modulation of fat metabolism and gut microbiota by resveratrol on high-fat diet-induced obese mice. Diabetes Metab Syndr Obes. Jung MJ, Lee J, Shin NR, Kim MS, Hyun DW, Yun JH, et al.
a Center for Chinese Medical Therapy lloss Systems Losz, Shanghai University of Traditional Chinese Medicine, OfrChina Amino acid synthesis pathway in humans zhoumm b Nutrilite Health Institute, Shanghai Lentils for vegetarian diet, China. c Research Center for Health and Nutrition, Shanghai University of Traditional Chinese Medicine, Shanghai, China. Resveratrol and quercetin, widely found in foods and vegetables, are plant polyphenols reported to have a wide range of biological activities. Despite their limited bioavailabilities, both resveratrol and quercetin are known to exhibit anti-inflammation and anti-obesity effects. We hypothesized that gut microbiota may be a potential target for resveratrol and quercetin to prevent the development of obesity.
die Genaue Antwort
Ist Einverstanden, diese lustige Mitteilung