Metformin dosage -
However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Keep from freezing. There is a problem with information submitted for this request. Sign up for free and stay up to date on research advancements, health tips, current health topics, and expertise on managing health.
Click here for an email preview. Error Email field is required. Error Include a valid email address. To provide you with the most relevant and helpful information, and understand which information is beneficial, we may combine your email and website usage information with other information we have about you.
If you are a Mayo Clinic patient, this could include protected health information. If we combine this information with your protected health information, we will treat all of that information as protected health information and will only use or disclose that information as set forth in our notice of privacy practices.
You may opt-out of email communications at any time by clicking on the unsubscribe link in the e-mail. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Mayo Clinic does not endorse companies or products.
Advertising revenue supports our not-for-profit mission. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press.
This content does not have an English version. This content does not have an Arabic version. Drugs and Supplements Metformin Oral Route. Sections Description and Brand Names Before Using Proper Use Precautions Side Effects. Products and services. Proper Use Drug information provided by: Merative, Micromedex ® This medicine usually comes with a patient information insert.
Thank you for subscribing! Sorry something went wrong with your subscription Please, try again in a couple of minutes Retry. Mayo Clinic Press Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press.
Mayo Clinic on Incontinence - Mayo Clinic Press Mayo Clinic on Incontinence The Essential Diabetes Book - Mayo Clinic Press The Essential Diabetes Book Mayo Clinic on Hearing and Balance - Mayo Clinic Press Mayo Clinic on Hearing and Balance FREE Mayo Clinic Diet Assessment - Mayo Clinic Press FREE Mayo Clinic Diet Assessment Mayo Clinic Health Letter - FREE book - Mayo Clinic Press Mayo Clinic Health Letter - FREE book.
Show the heart some love! Give Today. Help us advance cardiovascular medicine. Find a doctor. Explore careers. Sign up for free e-newsletters. About Mayo Clinic.
About this Site. Contact Us. Health Information Policy. Media Requests. News Network. Price Transparency. Medical Professionals. Clinical Trials. Short-term administration of metformin hydrochloride extended-release tablets may be sufficient during periods of transient loss of control in patients usually well-controlled on diet alone.
Metformin hydrochloride extended-release tablets must be swallowed whole and never crushed or chewed. Occasionally, the inactive ingredients of metformin hydrochloride extended-release tablets will be eliminated in the feces as a soft, hydrated mass.
See Patient information printed below. Recommended Dosing Schedule Adults - In general, clinically significant responses are not seen at doses below mg per day. However, a lower recommended starting dose and gradually increased dosage is advised to minimize gastrointestinal symptoms.
The usual starting dose of metformin hydrochloride extended-release tablet is mg once daily with the evening meal. Dosage increases should be made in increments of mg weekly, up to a maximum of mg once daily with the evening meal.
If glycemic control is not achieved on metformin hydrochloride extended-release tablets mg once daily, a trial of metformin hydrochloride extended-release tablets mg twice daily should be considered. In a randomized trial, patients currently treated with metformin hydrochloride tablets were switched to metformin hydrochloride extended-release tablets.
Results of this trial suggest that patients receiving metformin hydrochloride tablets treatment may be safely switched to metformin hydrochloride extended-release tablets once daily at the same total daily dose, up to mg once daily.
Following a switch from metformin hydrochloride tablets to metformin hydrochloride extended-release tablets, glycemic control should be closely monitored and dosage adjustments made accordingly Pediatrics — Safety and effectiveness of metformin hydrochloride extended-release tablets in pediatric patients have not been established.
Transfer From Other Antidiabetic Therapy When transferring patients from standard oral hypoglycemic agents other than chlorpropamide to metformin hydrochloride extended-release tablets, no transition period generally is necessary. When transferring patients from chlorpropamide, care should be exercised during the first two weeks because of the prolonged retention of chlorpropamide in the body, leading to overlapping drug effects and possible hypoglycemia.
Concomitant Metformin Hydrochloride Extended-Release Tablets and Oral Sulfonylurea Therapy in Adult Patients If patients have not responded to four weeks of the maximum dose of metformin hydrochloride extended-release tablets monotherapy, consideration should be given to gradual addition of an oral sulfonylurea while continuing metformin hydrochloride extended-release tablets at the maximum dose, even if prior primary or secondary failure to a sulfonylurea has occurred.
Clinical and pharmacokinetic drug-drug interaction data are currently available only for metformin plus glyburide glibenclamide. With concomitant metformin hydrochloride extended-release tablets and sulfonylurea therapy, the desired control of blood glucose may be obtained by adjusting the dose of each drug.
However, attempts should be made to identify the minimum effective dose of each drug to achieve this goal.
With concomitant metformin hydrochloride extended-release tablets and sulfonylurea therapy, the risk of hypoglycemia associated with sulfonylurea therapy continues and may be increased. Appropriate precautions should be taken.
See Package Insert of the respective sulfonylurea. If patients have not satisfactorily responded to one to three months of concomitant therapy with the maximum dose of metformin hydrochloride extended-release tablets and the maximum dose of an oral sulfonylurea, consider therapeutic alternatives including switching to insulin with or without metformin hydrochloride extended-release tablets.
Concomitant Metformin Hydrochloride Extended-Release Tablets and Insulin Therapy in Adult Patients. The current insulin dose should be continued upon initiation of metformin hydrochloride extended-release tablets therapy.
Metformin hydrochloride extended-release tablets therapy should be initiated at mg once daily in patients on insulin therapy.
For patients not responding adequately, the dose of metformin hydrochloride extended-release tablets should be increased by mg after approximately 1 week and by mg every week thereafter until adequate glycemic control is achieved.
The maximum recommended daily dose is mg for metformin hydrochloride extended-release tablets. Further adjustment should be individualized based on glucose-lowering response. Specific Patient Populations Metformin hydrochloride extended-release tablets are not recommended for use in pregnancy.
Metformin oral tablet Metformim in two forms: Bitter orange for liver health and extended-release. The immediate-release tablet is available Metformin dosage a Metformin dosage drug. The extended-release dosagd is available as Metformin dosage brand-name drugs Fortamet and Glumetza. Both tablet forms are available as generic drugs. Generics usually cost less than brand-name versions. In some cases, they may not be available in all strengths or forms as brand-name drugs. Metformin oral tablets are used to treat high blood sugar levels caused by type 2 diabetes.Metformin dosage -
Continue to take metformin even if you feel well. Do not stop taking metformin without talking to your doctor. This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
Be sure to follow all exercise and dietary recommendations made by your doctor or dietitian. It is important to eat a healthful diet. Take the missed dose as soon as you remember it.
However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule.
Do not take a double dose to make up for a missed one. Metformin may cause other side effects. Call your doctor if you have any unusual problems while taking this medication. Keep this medication in the container it came in, tightly closed, and out of reach of children.
Store it at room temperature and away from light, excess heat, and moisture not in the bathroom. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them.
However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. It is important to keep all medication out of sight and reach of children as many containers such as weekly pill minders and those for eye drops, creams, patches, and inhalers are not child-resistant and young children can open them easily.
To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location — one that is up and away and out of their sight and reach. In case of overdose, call the poison control helpline at If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at Your doctor will tell you how to check your response to this medication by measuring your blood sugar levels at home.
Follow these instructions carefully. If you are taking the extended-release tablets, you may notice something that looks like a tablet in your stool. This is just the empty tablet shell, and this does not mean that you did not get your complete dose of medication.
You should always wear a diabetic identification bracelet to be sure you get proper treatment in an emergency. Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription. It is important for you to keep a written list of all of the prescription and nonprescription over-the-counter medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements.
You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Generic alternatives may be available. Metformin pronounced as met for' min. Why is this medication prescribed? How should this medicine be used? Other uses for this medicine What special precautions should I follow?
What special dietary instructions should I follow? What should I do if I forget a dose? What side effects can this medication cause? What should I know about storage and disposal of this medication?
Brand names Brand names of combination products. IMPORTANT WARNING:. Swallow metformin extended-release tablets whole; do not split, chew, or crush them. Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.
Other uses for this medicine. What special precautions should I follow? Before taking metformin, tell your doctor and pharmacist if you are allergic to metformin, any of the ingredients of metformin liquid or tablets, or any other medications.
Ask your pharmacist or check the manufacturer's patient information for a list of the ingredients. tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking.
Your doctor may need to change the doses of your medications or monitor you carefully for side effects. tell your doctor if you have or have ever had any medical condition, especially those mentioned in the IMPORTANT WARNING section.
tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking metformin, call your doctor. tell your doctor if you eat less or exercise more than usual.
This can affect your blood sugar. Your doctor will give you instructions if this happens. This medication may cause changes in your blood sugar. If glycemic control is not achieved on metformin hydrochloride extended-release tablets mg once daily, a trial of metformin hydrochloride extended-release tablets mg twice daily should be considered.
In a randomized trial, patients currently treated with metformin hydrochloride tablets were switched to metformin hydrochloride extended-release tablets. Results of this trial suggest that patients receiving metformin hydrochloride tablets treatment may be safely switched to metformin hydrochloride extended-release tablets once daily at the same total daily dose, up to mg once daily.
Following a switch from metformin hydrochloride tablets to metformin hydrochloride extended-release tablets, glycemic control should be closely monitored and dosage adjustments made accordingly Pediatrics — Safety and effectiveness of metformin hydrochloride extended-release tablets in pediatric patients have not been established.
Transfer From Other Antidiabetic Therapy When transferring patients from standard oral hypoglycemic agents other than chlorpropamide to metformin hydrochloride extended-release tablets, no transition period generally is necessary.
When transferring patients from chlorpropamide, care should be exercised during the first two weeks because of the prolonged retention of chlorpropamide in the body, leading to overlapping drug effects and possible hypoglycemia. Concomitant Metformin Hydrochloride Extended-Release Tablets and Oral Sulfonylurea Therapy in Adult Patients If patients have not responded to four weeks of the maximum dose of metformin hydrochloride extended-release tablets monotherapy, consideration should be given to gradual addition of an oral sulfonylurea while continuing metformin hydrochloride extended-release tablets at the maximum dose, even if prior primary or secondary failure to a sulfonylurea has occurred.
Clinical and pharmacokinetic drug-drug interaction data are currently available only for metformin plus glyburide glibenclamide. With concomitant metformin hydrochloride extended-release tablets and sulfonylurea therapy, the desired control of blood glucose may be obtained by adjusting the dose of each drug.
However, attempts should be made to identify the minimum effective dose of each drug to achieve this goal. With concomitant metformin hydrochloride extended-release tablets and sulfonylurea therapy, the risk of hypoglycemia associated with sulfonylurea therapy continues and may be increased.
Appropriate precautions should be taken. See Package Insert of the respective sulfonylurea. If patients have not satisfactorily responded to one to three months of concomitant therapy with the maximum dose of metformin hydrochloride extended-release tablets and the maximum dose of an oral sulfonylurea, consider therapeutic alternatives including switching to insulin with or without metformin hydrochloride extended-release tablets.
Concomitant Metformin Hydrochloride Extended-Release Tablets and Insulin Therapy in Adult Patients. The current insulin dose should be continued upon initiation of metformin hydrochloride extended-release tablets therapy.
Metformin hydrochloride extended-release tablets therapy should be initiated at mg once daily in patients on insulin therapy. For patients not responding adequately, the dose of metformin hydrochloride extended-release tablets should be increased by mg after approximately 1 week and by mg every week thereafter until adequate glycemic control is achieved.
The maximum recommended daily dose is mg for metformin hydrochloride extended-release tablets. Further adjustment should be individualized based on glucose-lowering response.
Specific Patient Populations Metformin hydrochloride extended-release tablets are not recommended for use in pregnancy. Metformin hydrochloride extended-release tablet is not recommended in pediatric patients below the age of 17 years. The initial and maintenance dosing of metformin hydrochloride extended-release tablets should be conservative in patients with advanced age, due to the potential for decreased renal function in this population.
Any dosage adjustment should be based on a careful assessment of renal function. Generally, elderly, debilitated, and malnourished patients should not be titrated to the maximum dose of metformin hydrochloride extended-release tablets. Monitoring of renal function is necessary to aid in prevention of lactic acidosis, particularly in the elderly.
Postmarketing cases of metformin-associated lactic acidosis have resulted in death, hypothermia, hypotension, and resistant bradyarrhythmias.
The onset of metformin associated lactic acidosis is often subtle, accompanied only by nonspecific symptoms such as malaise, myalgias, respiratory distress, somnolence, and abdominal pain.
Risk factors for metformin-associated lactic acidosis include renal impairment, concomitant use of certain drugs e.
Official websites use. Metformin dosage A. Metformin dosage dodage belongs to an official government organization in the United States. gov website. Share sensitive information only on official, secure websites. Metformin may rarely cause a serious, life-threatening condition called lactic acidosis.
Es kommt mir ganz nicht heran.