Free Radic Biol Med ; High protein snacks enhances immune and haemopoietic Pycnogeno in senescence-accelerated mice. Bratisl Lek Listy. Fractionated Coconut Oil. Bwnefits include limiting the buildup of fat, reducing oxidative stress and the likelihood of blood clots, and improving venous function 424344 Continue the Conversation Does the vaginal lotion get used at night and is there a discharge from using it?

Pycnogenol benefits -

A small study examined the effects of pine bark extract in treating cardiovascular risk factors associated with menopause. Perimenopausal women who took pine bark extract for eight weeks noticed decreased cholesterol and triglyceride levels.

High levels of both of these are considered risk factors for heart disease. A review indicates that pine bark extract can be used to treat metabolic syndrome and related disorders such as obesity , diabetes , and high blood pressure.

The review found evidence that pine bark extract may:. Similar to its neuroprotective benefits, the metabolic benefits of pine bark extract seem to be related to its antioxidant and anti-inflammatory properties. Pine bark extract is usually taken by mouth in capsule form.

However, it can also be used topically. You can gradually increase how much you take once you get a better idea of how your body reacts to it. As a skin powder, however, you can use it safely for up to six weeks.

Work with your pediatrician to see if there are contraindications for each child. While pine bark extract is thought to be safe for children, they should only take it for a few weeks at a time. After taking a break for one to two weeks, they can start taking it again for several weeks.

If possible, try to get pine bark extract from a local supplier, such as a health food store. The staff there can often answer any questions you have and give you more information about specific brands.

You should also do additional research or talk to your doctor before taking pine bark extract if you also take:. While pine bark extract is a natural supplement, it can have powerful effects on your health, both positive and negative.

Also, be sure to talk with your doctor first if you have an underlying medical condition or take other medications. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. Learn more about how to get even skin tone.

Clearer skin, healthier hair — there are a lot of claims about the health benefits of biotin. We take a look at what the science actually says.

Prenatal nutrition can be confusing. This article explains which supplements are believed to be safe during pregnancy and which ones you should avoid. Some people seek to manage ADHD symptoms through an ADHD diet.

Molecular evidence substantiating such effects, however, is scarce. In the present study we investigated whether nutritional supplementation of women with the standardized pine bark extract Pycnogenol® will improve their cosmetic appearance and relate these effects to expression of corresponding molecular markers of their skin.

Materials and methods: For this purpose 20 healthy postmenopausal women were supplemented with Pycnogenol for 12 weeks. Before, during and after supplementation, their skin condition was assessed i by employing non-invasive, biophysical methods including corneometry, cutometry, visioscan and ultrasound analyses and ii by taking biopsies and subsequent PCR for gene expression analyses related to extracellular matrix homeostasis.

Results: Pycnogenol supplementation was well tolerated in all volunteers. Pycnogenol is an antioxidant-rich herbal supplement made from pine bark. It may be helpful for people with OA and could help lower the risk of heart disease and diabetes.

Clinical trials using pycnogenol are very limited, though. Stronger data are needed before it can be recommended for most conditions.

Pycnogenol has not been proven safe during pregnancy or breastfeeding or for children under 6. It also may interact with blood pressure and diabetes medicines, NSAIDs, and some cancer medicines. Pycnogenol has been studied for many conditions, from asthma to traumatic brain injury TBI , but there's not much evidence it works.

Some reviews suggest it reduced osteoarthritis pain or prevented heart disease or diabetes, but more clinical trials are needed. Probably not. In fact, a small study of postmenopausal females showed that pycnogenol promoted hair growth. In small clinical trials, pycnogenol has been shown to protect against ultraviolet UV rays, improve skin elasticity , and reduce melasma overpigmentation of the skin.

Small studies suggest it may be helpful in males with erectile dysfunction who also take antidepressants or have diabetes. A review of clinical trials determined that there isn't enough evidence to know whether pycnogenol improves erectile function or other aspects of sexual health.

Robertson NU, Schoonees A, Brand A, et al. Pine bark Pinus spp. extract for treating chronic disorders. Cochrane Database Syst Rev. Sahebkar A. A systematic review and meta-analysis of the effects of pycnogenol on plasma lipids.

J Cardiovasc Pharmacol Ther. Malekahmadi M, Moradi Moghaddam O, Islam SMS, et al. Evaluation of the effects of pycnogenol French maritime pine bark extract supplementation on inflammatory biomarkers and nutritional and clinical status in traumatic brain injury patients in an intensive care unit: A randomized clinical trial protocol.

Published Feb Verlaet AA, Ceulemans B, Verhelst H, et al. Effect of Pycnogenol® on attention-deficit hyperactivity disorder ADHD : Study protocol for a randomised controlled trial. Belcaro G, Cornelli U, Luzzi R, et al. Pycnogenol® supplementation improves health risk factors in subjects with metabolic syndrome.

Phytother Res. Simpson T, Kure C, Stough C. Assessing the efficacy and mechanisms of pycnogenol® on cognitive aging from in vitro animal and human studies. Front Pharmacol.

Becit M, Aydin S. An in vitro study on the interactions of Pycnogenol® with Cisplatin in human cervical cancer cells. Turk J Pharm Sci. Ekinci B, Suleyman B, Mammadov R, et al.

Beneficial interaction of pycnogenol with indomethacin in rats. Gen Physiol Biophys. Malekahmadi M, Moradi Moghaddam O, Firouzi S, et al. Effects of pycnogenol on cardiometabolic health: A systematic review and meta-analysis of randomized controlled trials.

Pharmacol Res. Ross SM. Allergic Rhinitis: A Proprietary Extract of Pinus pinaster Aiton Pycnogenol Is Found to Improve the Symptoms Associated With Allergic Rhinitis.

Holist Nurs Pract. Zhao H, Wu J, Wang N, et al. Oral pycnogenol® intake benefits the skin in urban Chinese outdoor workers: A randomized, placebo-controlled, double-blind, and crossover intervention study. Skin Pharmacol Physiol. Pourmasoumi M, Hadi A, Mohammadi H, Rouhani MH.

Effect of pycnogenol supplementation on blood pressure: A systematic review and meta-analysis of clinical trials. Belcaro G, Luzzi R, Dugall M, Ippolito E, Saggino A.

Pycnogenol® improves cognitive function, attention, mental performance and specific professional skills in healthy professionals aged J Neurosurg Sci. Chan V, Wang L, Allman-Farinelli M.

Efficacy of Functional Foods, Beverages, and Supplements Claiming to Alleviate Air Travel Symptoms: Systematic Review and Meta-Analysis. Published Mar Vinciguerra G, Belcaro G, Bonanni E, et al. Evaluation of the effects of supplementation with Pycnogenol® on fitness in normal subjects with the Army Physical Fitness Test and in performances of athletes in the minute triathlon.

J Sports Med Phys Fitness. Malekahmadi M, Shadnoush M, Islam SMS, et al. The effect of French maritime pine bark extract supplementation on inflammation, nutritional and clinical status in critically ill patients with traumatic brain injury: A randomized controlled trial.

Bnefits has the Pycnogebol sourcing Pycnogebol in the Pycnogenol benefits industry ebnefits we almost exclusively link Pycnogenol benefits medically Pycnogenol benefits studies, usually on PubMed. We believe that the Allergy prevention methods accurate information benefitts found directly in the scientific source. We are dedicated to providing the most scientifically valid, unbiased, and comprehensive information on any given topic. Our team comprises of trained MDs, PhDs, pharmacists, qualified scientists, and certified health and wellness specialists. Our science team is put through the strictest vetting process in the health industry and we often reject applicants who have written articles for many of the largest health websites that are deemed trustworthy. You love your Pycnogenol benefits walks and watching the benefita Pycnogenol benefits trees sway rhythmically benrfits the wind. But some pine trees are Pycnogenol benefits beneflts more than Vegan cooking videos peaceful walks in the woods. Extracted from the tree bark, pycnogenol ® gives pine trees a whole new definition. You take in the smell of the fresh air— a mixture of rain, dirt, and wet wood. You hear the sound of the branches rustling under your feet. All with nature as the most enchanting backdrop for your scene.

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Pycnogenol benefits -

According to some researchers, when you take Pycnogenol [ 8 ]:. Research suggests that Pycnogenol may protect cells in the body against oxidative stress.

It also may help regenerate and maintain vitamin C and E levels while also potentially increasing nitric oxide levels, which may relax and protect blood vessels [ 1 ]. Clinical research suggests that Pycnogenol is possibly effective for improving athletic performance. According to researchers, it may help prevent the rise in free radicals typically seen after exercise, which could cause muscle fatigue and damage [ 9 ].

Finally, research suggests that Pycnogenol may improve triathlon time while possibly reducing cramps and post-running pain [ 10 ].

The researchers of the study propose that pycnogenol may reduce pain and cramps during retraining and rehabilitation in people with blood vessel problems [ 11 ]. Based on another study of 6 trained and 7 untrained people, an antioxidant combination product containing Pycnogenol Lactaway may increase endurance.

This supplement may also increase muscle endurance and performance after a single pre-exercise dose according to a study of 9 cyclists [ 12 , 13 ]. A randomized placebo-controlled trial of 60 children with mild-to-moderate asthma found that those who took Pycnogenol may be able to reduce or discontinue their use of rescue inhalers more often than the placebo group [ 15 ].

Researchers suggest that Pycnogenol may reduce cough, night-awakenings, improve airway flow, and the need for additional asthma medication [ 16 ]. A trial of 39 people with hay fever found that Pycnogenol may reduce nose and eye symptoms.

In the study, the placebo group had higher IgE antibodies to the birch allergen than those who took Pycnogenol during the allergy season [ 17 ]. Another clinical trial of 76 people with allergic asthma also suggests that Pycnogenol may reduce IgE antibodies and asthma symptoms [ 18 , 16 ].

Importantly, all studies found that Pycnogenol has to be taken at least 5 weeks before the allergy season in order to see potential benefits, with the best results in those who take it weeks ahead.

One study suggests that Pycnogenol has no effect when given just 3 weeks beforehand, as it possibly requires a lag time to stabilize the immune response [ 17 ]. Researchers suggest it may boost sustained attention, memory, executive functions, mood, and reduce oxidative stress [ 19 ].

A trial of 53 students found that pycnogenol may improve cognitive function, memory, attention, mood, and mental performance after 8 weeks [ 20 ]. Pycnogenol also potentially improved cognitive function in 78 people with mild cognitive impairment.

Enzogenol, a slightly different pine bark extract, improved cognitive function in a clinical trial of 42 older men after 5 weeks of supplementation [ 23 ].

Researchers suggest that it may have stronger benefits than elastic compression stockings. In the study, women taking Pycnogenol were more satisfied and compliant to the regimen [ 24 ]. When pycnogenol cream was added to oral supplements in a small study of 18 people with vein ulcers, it helped ulcers heal more quickly [ 26 ].

One study of found that Pycnogenol may help prevent edema and ankle swelling from long flights [ 27 ]. Pycnogenol improved symptoms, circulation, and reduced complications in people with deep vein thrombosis blot clots in deep leg veins in a month study. It had the best results when combined with compression stockings, but worked just as well alone [ 28 ].

The following purported benefits of Pycnogenol are only supported by limited, low-quality clinical studies. There is insufficient evidence to support the use of Pycnogenol for any of the uses listed below. Remember to speak with a doctor before taking Pycnogenol. It should never be used as a replacement for approved medical therapies.

In a study of 50 overweight people, a combination product Pycnogenol, Madeglucyl, and starches called Glucaffect reduced weight, BMI, blood glucose, and HbA1C after 8 weeks [ 30 ]. A number of clinical trials suggest that Pycnogenol may lower blood glucose if taken daily for at least 12 weeks.

It also may help those on blood pressure medications to reduce their dose [ 32 ]. In another trial, 30 people with type 2 diabetes received a range of pycnogenol doses.

However, in all the above studies insulin levels did not change. In 24 people with early eye damage from diabetes, Pycnogenol improved vision, reduced eye swelling, and improved circulation in the eye after 2 months. Used early on, it may prevent eye damage and blindness from diabetes [ 34 ].

A trial of 86 people with eye damage from diabetes found that antioxidant therapy including pycnogenol, vitamin E , and Coenzyme Q10 may improve eye health and reduce reactive oxygen species levels [ 35 ].

According to some researchers, Pycnogenol may lower blood pressure by relaxing blood vessels, reducing free radicals, and lowering inflammation. In the study, many of the participants on Pycnogenol reduced their dosage of high-blood-pressure medication nifedipine [ 37 ].

A Pycnogenol combination product with l-arginine , alpha lipoic acid , B vitamins, and vitamin K2 may help protect the blood vessels and reduce high homocysteine levels, according to a trial of 25 people [ 39 ].

A study of 32 people with heart failure lasting 12 weeks suggests that a combination of Pycnogenol with CoQ10 PycnoQ10 may improve blood pressure, heart function, edema, and capacity for physical activity [ 40 ]. Researchers suggest this effect may be due to reduced dopamine and adrenaline levels and increased glutathione levels.

In a study of 61 ADHD children, pycnogenol reduced hyperactivity, improved attention, and motorics after 1 month. But a month after pycnogenol was stopped, the symptoms came back, suggesting that it may need to be used regularly to achieve the benefits [ 41 ].

A trial of children with ADHD found that Pycnogenol may improve attention, possibly by increasing the total antioxidant status and reducing DNA damage.

In another study, Pycnogenol increased glutathione levels and total antioxidants after a month in children with ADHD [ 42 , 43 ]. However, a study of 24 adults with ADHD found that pycnogenol did not improve ADHD symptoms better than placebo. Researchers from the study suggest that low Pycnogenol dosage and short study duration may explain the lack of benefits [ 44 ].

According to a large analysis, Pycnogenol may reduce osteoarthritis symptoms and pain short-term [ 45 , 46 ]. Researchers suggest that it may epigenetically turn off genes responsible for joint damage ADAMTS as well as reduce inflammation enzymes MMP3 and cytokines IL 1-beta [ 47 , 48 ].

In one clinical trial of osteoarthritis patients, pycnogenol reduced pain, stiffness, swelling, and improved joint function after 3 months. In a smaller study of 58 people, pycnogenol reduced the inflammatory marker CRP [ 49 , 50 ].

Subjects in the study that took Pycnogenol ended up taking fewer painkillers [ 51 ]. One study found that Pycnogenol may reduce the activity of the inflammatory enzymes COX1 and COX2 , similar to how NSAID drugs work.

According to the lab results of 10 volunteers, a higher Pycnogenol dose mg may impact these enzymes after just 30 minutes [ 52 ]. In 7 volunteers, Pycnogenol mg for 5 days may reduce the activity of a crucial inflammatory gene NF-κB [ 53 ].

According to a study of 11 patients with lupus, pycnogenol may reduce symptoms, inflammation, and oxidative stress [ 54 ]. Chewing gum with Pycnogenol 2. A systematic review of 14 studies found that Pycnogenol gum or mouthwashes may reduce dental plaque, but the quality of evidence is low [ 58 , 59 ].

In the study, it reduced cold symptoms and complications, the number of lost working days, and the use of over-the-counter medications compared to those who did not supplement with the extract [ 60 ].

A trial of 84 people found that both Pycnogenol oral supplements and creams 0. In contrast, bleeding still occurred in the control group [ 61 ]. Pycnogenol may help reduce symptoms of melasma, a form of hyperpigmentation, possibly because it protects against UV rays.

Pycnogenol supplementation reduced skin redness from UV rays in a trial of 21 people over 8 weeks. With time, the participants were able to handle more UV radiation without experiencing skin damage [ 63 ].

In a study of 20 postmenopausal women, 12 weeks of pycnogenol supplementation improved hydration and elasticity of the skin. It also may increase the activity of genes that make collagen and hyaluronic acid in the body [ 64 ]. In the second trial, people with mild osteoarthritis of the knee were randomly allocated to receive either mg Pycnogenol® or a placebo for three months.

Osteoarthritis OA is the most common form of arthritis. It can cause joint pain and stiffness. Learn about the causes, symptoms and treatments. Versus Arthritis About arthritis Complementary and alternative treatments Types of complementary treatments Pine bark extracts. Pine bark extracts. Download complementary and alternative medicines report Download.

Print this page Print. Share this page Share Share on Facebook Tweet LinkedIn. What is it? Family: Herbal extract and nutritional supplement Scientific name: Pinus pinaster ssp. Atlantica Other names: French pinus maritime bark, Pycnogenol®, pinus maritima, pygenol, PYC Pinus pinaster is a type of pine tree native to France.

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Pycnogenol benefits PPycnogenol supplement studied for its benefiys on Assessing water composition and disease prevention. Pycnogenol is an antioxidant derived from French maritime pine Pinus maritima tree High protein snacks. It's been studied for benefts High protein snacks varied as heart disease and attention deficit hyperactivity disorder ADHD. However, data on its efficacy and safety are limited. This article discusses pycnogenol's evidence-based benefits and risks, including drug interactions and precautions to consider before adding this supplement to your medicine cabinet. Pycnogenol is an herbal extract made from the bark of the French maritime pine Pinus pinaster. French maritime pine is native to the western Mediterranean.