Supolementation pretreatment induces Supplementtion and an antioxidant Herbal medicine for wellness and prevents hemin-induced Herbal medicine for wellness in primary cultures of Organic detox programs granule supplementatiln of rats. Information about a therapy, service, product or treatment does not in any way endorse or support such therapy, service, product or treatment and is not intended to replace advice from your doctor or other registered health professional. If you need to take a supplement, seek advice from your doctor or dietitian and choose supplements that contain all nutrients at the recommended levels.

Antioxidant supplementation -

Many studies have shown that taking supplements that contain concentrated doses of antioxidants may benefit certain aspects of health. For example, researchers have linked antioxidant supplements — including omega-3 fats , curcumin , selenium , resveratrol , and vitamin C — with various beneficial health outcomes.

However, although certain antioxidants may deliver health benefits when a person takes them for a specific reason, this does not mean that taking supplemental antioxidants is always safe or necessary.

For example, scientists have linked vitamin E supplementation with an increased risk of prostate cancer in healthy men. Similarly, studies have linked beta carotene supplementation with an increased risk of lung cancer in smokers. Research has also found no clear benefit of antioxidant supplements on disease risk.

Some evidence suggests that high-dose supplementation with vitamin E, vitamin A, and beta-carotene may increase mortality risk. Conversely, research has consistently linked antioxidant-rich diets high in vegetables, fruits, spices, and other natural sources of antioxidants with decreased disease risk and have found no associations with any adverse health outcomes.

For this reason, experts suggest that people should focus on consuming antioxidants through the foods they eat. They do not recommend that people take high-dose antioxidants supplements unless specifically recommended by a healthcare provider.

There is no doubt that consuming a diet high in antioxidant-rich foods is beneficial for health and may help prevent disease development. It is best to avoid high-dose antioxidant supplements unless a trusted healthcare provider prescribes or recommends them. The best way to take in antioxidants is through foods and beverages, such as vegetables, fruits, nuts, fish, spices, and tea.

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Random-effects model meta-regression analyses were performed to assess sources of intertrial heterogeneity. Seventy-eight randomised trials with , participants were included.

Fifty-six trials including , participants had low risk of bias. Fifty-two trials included 80, participants with various diseases in a stable phase. The mean age was 63 years range 18 to years. Of the 78 trials, 46 used the parallel-group design, 30 the factorial design, and 2 the cross-over design.

All antioxidants were administered orally, either alone or in combination with vitamins, minerals, or other interventions. The duration of supplementation varied from 28 days to 12 years mean duration 3 years; median duration 2 years.

In meta-regression analysis, the risk of bias and type of antioxidant supplement were the only significant predictors of intertrial heterogeneity. Meta-regression analysis did not find a significant difference in the estimated intervention effect in the primary prevention and the secondary prevention trials.

This effect was confirmed by trial sequential analysis. In univariate meta-regression analysis, the dose of vitamin A was significantly associated with increased mortality RR 1. Language: English Deutsch Español فارسی Français Hrvatski Bahasa Malaysia Polski Português Русский ภาษาไทย 繁體中文. If you found this evidence helpful, please consider donating to Cochrane.

We are a charity that produces accessible evidence to help people make health and care decisions. Authors' conclusions:. Antioxidants are most abundant in plant foods, and include vitamins C, A and E, beta-carotene and lycopene.

A diet high in antioxidants may reduce the risk of many diseases simply by mopping up damaging free radicals circulating in the blood stream. For example, men who eat a lot of lycopene an antioxidant found in tomatoes may be less likely to develop prostate cancer. Not all free radicals are damaging , and some are even used to attack viruses or bacteria to protect us from harm.

However, others can damage cells and contribute to conditions such as heart disease and some cancers. Most of us can get all the nutrients we need from food, rather than taking supplements.

Vegetables and fruit tend to be packed full of antioxidants. Eating a wide variety of them can help ensure you get a diverse range of different antioxidants to optimise your health.

There are hundreds of antioxidants in not only fruit and vegetables, but nuts, seeds, olive oil and wholegrains. The Australian Dietary Guidelines outline the types of foods you should be eating to reduce your risk of diet-related conditions and chronic diseases.

In some cases, your doctor may recommend you take antioxidant supplements if your diet is inadequate. The only reason to take supplements is if you have a deficiency. For example, vegetarians might need iron or vitamin B12, or people with osteoporosis might need extra calcium and vitamin D.

If you follow a healthy balanced diet, and you have no vitamin deficiencies, adding antioxidant supplements is unlikely to make any difference to your health. Rigorous scientific studies involving more than , people tested whether antioxidant supplements played a role in preventing chronic diseases, like cardiovascular diseases, cancer, and cataracts.

In most instances, supplementing with antioxidants did not reduce the risks of developing these diseases. In fact, some supplements can be toxic in large doses, interact with other medications, and can actually increase the risk of developing certain diseases.

There are no current concerns about the levels of antioxidants we consume in food. Antioxidant foods for healthy glowing skin: Eat your way to better looking skin. You can find antioxidant supplements in different forms, including multivitamins, antioxidant blends, tablets, vitamins, gummies and powders to mix into drinks or sprinkle on foods.

Taking too many antioxidant supplements, especially vitamins C and E can interfere with how your body adapts to exercise and even reduce some of the health benefits of exercise. Studies have even shown that antioxidant supplements may even increase the risk of certain cancers.

Some can interfere with cancer treatment medications and therapies so check with your doctor before you start taking any. Some antioxidants supplements such as Vitamin A may even increase the risk of birth defects if taken in high doses.

If you are pregnant, always check with your doctor before you start taking any regular supplements.

Antioxiadnt Antioxidant supplementation June This article Chronic inflammation treatment created by familydoctor. org supplementatkon staff Antioxidant supplementation reviewed by Leisa Bailey, MD. Viruses and infections attack them. Free radicals also can damage your cells and DNA. Some cells can heal from the damage, while others cannot. Supplmeentation to navigation. Previous research ssupplementation Antioxidant supplementation and physiological Electronic devices online suggests that antioxidant supplements have beneficial Antioxidant supplementation that may prolong life. Supplementatioj observational studies also suggest that antioxidant supplements may prolong life, whereas other observational studies demonstrate neutral or harmful effects. Our Cochrane review from demonstrated that antioxidant supplements seem to increase mortality. This review is now updated. The present systematic review included 78 randomised clinical trials.

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