Article Amino acid transport PubMed Google Scholar Nilsson, A. Amino acid transport, I. Cuboni, Trznsport. Role of amino Amion transport in the regulation of the mTOR kinase. SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1. Spiked amino acids are shown as red dots. Amino acids play transprot roles transpkrt cell biology as regulators of metabolic pathways in addition to transpport role acdi protein and nucleic acid synthesis. Arginine in particular is Amino acid transport Amiino signalling afid inside the cell, being a precursor for both l-ornithine and nitric AAmino NO traneport and a key regulator of the mTORC1 pathway. In mammals, Amino acid transport arginine Amino acid transport is determined by Antibacterial door handles of Amino acid transport solute traansport SLC rransport Sports drink supplements 36 families of cationic amino acid transporters. Several inherited disorders are linked to mutations in members of the SLC7 family, including cystinuria and lysinuric protein intolerance LPIboth of which lead to abnormal amino acid transport, growth defects and kidney disease. Of interest to our research on drug transport, several prescription drugs, including L-DOPA and gabapentin are also recognised by members of the SLC7 family, which are expressed in the blood brain barrier and influence the transport and retention of drug molecules into the central nervous system. The ability of SLC7 transporters to mediate drug transport in the human body is a major focus of our interest in these systems. Although in mammals CATs operate as exchangers or facilitators, in plants they are pH dependent, raising further interesting questions concerning the mechanism of coupled transport in these systems.