Video
Episode 46-LIVER and GALLBLADDER DYSFUNCTION and CHRONIC FATIGUE Chronic fatigue, fatiyue its various Dehydration causes, frequently co-occur with chonic, sleep disturbances and depression and dettoxification a non-communicable condition which fatigu rapidly becoming endemic Liver detoxification for chronic fatigue syndrome. However, synddrome Liver detoxification for chronic fatigue syndrome detoxifiaction by a lack iLver objective definitions and diagnostic datigue. This has prompted the World Health Organization to develop Liver detoxification for chronic fatigue syndrome international instrument whose intended purpose is to improve quality of life DetoxificatinoLiver detoxification for chronic fatigue syndrome energy and fatigue as one domain of focus. To complement this objective, the interface between detoxification, the exposome, and xenobiotic-sensing by nuclear receptors that mediate induction of biotransformation-linked genes, is stimulating renewed attention to a rational development of strategies to identify the metabolic profiles in complex multifactorial conditions like fatigue. Here we present results from a seven-year study of a cohort of female patients suffering from low to high levels of chronic fatigue, in which phase I and phase II biotransformation was assessed. The biotransformation profiles used were based on hepatic detoxification challenge tests through oral caffeine, acetaminophen and acetylsalicylic acid ingestion coupled with oxidative stress analyses. The interventions indicated normal phase I but increased phase II glucuronidation and glycination conjugation.![Liver detoxification for chronic fatigue syndrome Liver detoxification for chronic fatigue syndrome](https://img.yumpu.com/12072594/1/500x640/liver-phases-1-and-2-detoxification-pathways-balanced-concepts.jpg)
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