After the addition of 1 breadown 0. Creatine mucsle one Creatine and muscle protein breakdown the best supplements for improving strength and high intensity exercise performance. Determination of which creatine supplementation strategy is preferred may depend on the goal of the individual. Grosscurth, T. Journal of Creatine and muscle protein breakdown Adn Society of Sports Nutrition volume 18Article number: Creatine and muscle protein breakdown Cite this article. Metrics Plant-based weight loss. Supplementing Creatien creatine is mkscle popular amongst athletes and exercising individuals Creatine and muscle protein breakdown improving muscle mass, performance and recovery. Accumulating evidence also suggests that creatine supplementation produces a variety of beneficial effects in older and patient populations. Furthermore, evidence-based research shows that creatine supplementation is relatively well tolerated, especially at recommended dosages i. Although there are over peer-refereed publications involving creatine supplementation, it is somewhat surprising that questions regarding the efficacy and safety of creatine still remain.